Norfloxacin Impurity 24 CAS 1415841-37-0
| CAS No. | 1415841-37-0 |
| Molecular Formula | C19H24FN3O3 |
| Molecular Weight | 361.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Norfloxacin Impurity 24.
As a process- or degradation-related impurity, Norfloxacin Impurity 24 (CAS 1415841-37-0, C19H24FN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C19H24FN3O3, Norfloxacin Impurity 24 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 361.41 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H24FN3O3 |
| Molecular Weight | 361.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Norfloxacin Standards
- Norfloxacin Impurity 49 (CAS CATO-C4X-146849)
- Norfloxacin Impurity C25 (CAS 74011-47-5)
- Norfloxacin EP Impurity G (CAS 70459-04-0)
- Norfloxacin Impurity 43 (CAS CATO-C4X-146843)
- Norfloxacin Impurity 54 (CAS CATO-C4X-146854)
- Norfloxacin Impurity 55 (CAS CATO-C4X-146855)
- Norfloxacin EP Impurity E (CAS 75001-85-3)
- Norfloxacin EP Impurity F (CAS 67681-84-9)
Recommended Standards
- Citalopram Impurity 66 (CAS CATO-C4X-110966)
- Pefloxacin Impurity 1 (CAS 81530-83-8)
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