Crizotinib impurity 24 CAS 141699-59-4
| CAS No. | 141699-59-4 |
| Molecular Formula | C11H21NO5S |
| Molecular Weight | 279.35 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Crizotinib impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Crizotinib impurity 24 (CAS 141699-59-4) is a certified pharmaceutical impurity reference standard with the molecular formula C11H21NO5S and a molecular weight of 279.35 g/mol.
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, Crizotinib impurity 24 is typically white to off-white crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 279.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C11H21NO5S |
| Molecular Weight | 279.35 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 2.0 |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Crizotinib Standards
- Crizotinib impurity 15 (CAS 1175708-03-8)
- Crizotinib impurity 33 (CAS CATO-C4X-102533)
- Crizotinib Impurity 69 (CAS CATO-C4X-102569)
- Crizotinib Impurity 71 (CAS CATO-C4X-102571)
- Crizotinib impurity 18 (CAS 2322921-92-4)
- Crizotinib Impurity 62 (CAS CATO-C4X-102562)
- Crizotinib Impurity 11 (CAS 1448326-32-6)
- Crizotinib impurity 11 (CAS 1269429-29-9)
Recommended Standards
- Argatroban Impurity 76 (CAS CATO-C4X-100776)
- Imatinib Impurity 69 (CAS 404577-34-0)
- Argatroban Impurity 75 (CAS CATO-C4X-100775)
- Fudosteine impurity 79 (CAS CATO-C4X-144779)
- Drospirenone EP Impurity E (CAS 90457-65-1)
- Pomalidomide Impurity 47 (CAS 885278-16-0)
- Ropivacaine EP Impurity E (CAS 265120-58-9)
- (2,5-Dichlorophenyl)(2-(morpholinomethyl)phenyl)methanone (CAS 898751-05-8)
- Aripiprazole Impurity 34 (CAS 39512-50-0)
- Tert-butyl 3-(((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2-yl)oxy)methyl)pyrrolidine-1-carboxylate (CAS 1310404-72-8)
- Sodium (2S,3S,4S,5R,6S)-6-((6-chloro-1H-indol-3-yl)oxy)-3,4,5-trihydroxytetrahydro-2H-pyran-2-carboxylate (CAS 216971-56-1)
- Methyl 3-{[2-(diethylamino)ethyl]amino}butanoate (CAS 1155162-02-9)
- (S)-3-Amino-4-hydroxybutanoic acid hydrochloride (CAS 1245645-62-8)
- Semaglutide impurity 104(Fmoc-D-His-Aib) (CAS 2171211-18-8)
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