Pyronaridine Impurity 2 CAS 1422180-92-4
| CAS No. | 1422180-92-4 |
| Molecular Formula | C12H6Cl2N2O |
| Molecular Weight | 265.09 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Pyronaridine Impurity 2 (CAS 1422180-92-4), a pharmacopoeial impurity reference standard (molecular formula C12H6Cl2N2O, MW 265.09 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Pyronaridine Impurity 2 (C12H6Cl2N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 265.09 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Pyronaridine Impurity 2 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H6Cl2N2O |
| Molecular Weight | 265.09 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Pyronaridine Standards
- Pyronaridine Impurity 3 (CAS CATO-C4X-29783)
- Pyronaridine Impurity 20 (CAS CATO-C4X-297820)
- Pyronaridine Impurity 12 (CAS CATO-C4X-297812)
- Pyronaridine Impurity 10 (CAS 6626-40-0)
- Pyronaridine Impurity 16 (CAS 81935-64-0)
- Pyronaridine Impurity 1 (CAS CATO-C4X-29781)
- Pyronaridine Impurity 7 (CAS CATO-C4X-29787)
- Pyronaridine Impurity 11 (CAS CATO-C4X-297811)
Recommended Standards
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- Sodium Cromoglicate Impurity 8 (CAS 16130-28-2)
- Methyl 5-acetamido-2-chloro-4-methoxybenzoate (CAS 1629269-87-9)
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- 2-methyl-1H-indazol-3(2H)-one (CAS 1848-40-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com