Erlotinib Impurity 114 CAS 14235-81-5

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.14235-81-5
Molecular FormulaC8H7N
Molecular Weight117.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Erlotinib Impurity 114 CAS 14235-81-5 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 117.15 g/mol gives Erlotinib Impurity 114 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Erlotinib Impurity 114 (CAS 14235-81-5), a pharmacopoeial impurity reference standard (molecular formula C8H7N, MW 117.15 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Erlotinib Impurity 114 (C8H7N) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Erlotinib Impurity 114 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC8H7N
Molecular Weight117.15 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1961
Nitrogen Atoms1

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