Erlotinib Impurity 120 CAS 54060-30-9

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.54060-30-9
Molecular FormulaC8H7N
Molecular Weight117.15 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Erlotinib Impurity 120 CAS 54060-30-9 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 117.15 g/mol gives Erlotinib Impurity 120 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Erlotinib Impurity 120 (CAS 54060-30-9) is a certified pharmaceutical impurity reference standard with the molecular formula C8H7N and a molecular weight of 117.15 g/mol.

Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, Erlotinib Impurity 120 is typically off-white to pale yellow liquid. Its solid-state physicochemical attributes — including a molecular weight of 117.15 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H7N
Molecular Weight117.15 g/mol
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in methanol, acetonitrile, DMSO
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)6.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1972
Nitrogen Atoms1

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