Upadacitinib Impurity 70 CAS 1428243-25-7
| CAS No. | 1428243-25-7 |
| Molecular Formula | C15H19NO4 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 448.56 g/mol gives Upadacitinib Impurity 70 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Upadacitinib Impurity 70 (CAS 1428243-25-7) is a certified pharmaceutical impurity reference standard with the molecular formula C15H19NO4C12H13N and a molecular weight of 448.56 g/mol.
The molecular framework of Upadacitinib Impurity 70 (C15H19NO4C12H13N) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Upadacitinib Impurity 70 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C15H19NO4 C12H13N |
| Molecular Weight | 448.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1991 |
| Nitrogen Atoms | 2 |
Related Upadacitinib Standards
- Upadacitinib Impurity 53 (CAS 1046861-47-5)
- Upadacitinib Impurity 218 (CAS 117718-83-9)
- Upadacitinib Impurity 17 (CAS 1201186-54-0)
- Upadacitinib Impurity 15 (CAS 1201187-44-1)
- Upadacitinib Impurity 2 (CAS 1201187-46-3)
- Upadacitinib Impurity 28 (CAS 1310726-59-0)
- Upadacitinib (CAS 1310726-60-3)
- Upadacitinib Impurity 18 (CAS 1428243-24-6)
Recommended Standards
- Acetazolamide EP Impurity F (CAS 80495-47-2)
- Dienogest EP Impurity H (CAS 16669-06-0)
- Cariprazine Impurity 54 (CAS CATO-C4X-240854)
- 4-(2,3-Difluorophenyl)benzoic acid (CAS 505082-93-9)
- 1-chloranyl-4-(2-nitro-1-phenyl-propyl)benzene 1-chloro-4-(2-nitro-1-phenylpropyl)benzene 586-39-0 A831961 (CAS 586-39-0)
- Chlorquinaldol impurity 3 (CAS 37026-23-6)
- Tucatinib Impurity 17 (CAS CATO-C4X-260517)
- Methyl 3-nitrodibenzo[b,e][1,4]dioxine-1-carboxylate (CAS 924831-72-1)
- N4-(2-Chlorophenyl)quinazoline-4,6-diamine (CAS 1428063-70-0)
- D-Pro38-Tirzepatide (CAS CATO-CPTD788901)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com