Chloroquine Diphosphate CAS 50-63-5
| CAS No. | 50-63-5 |
| Molecular Formula | C18H26ClN3 |
| Molecular Weight | N/A |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies Chloroquine Diphosphate (CAS 50-63-5), a certified reference material (molecular formula C18H26ClN3H3O4P, MW 417.87 g/mol) for analytical method development and quality control.
Chloroquine Diphosphate (C18H26ClN3H3O4P) contains a steroid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H26ClN3 2*H3O4P |
| Molecular Weight | 417.87 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1957 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloroquine Standards
- Chloroquine-d4 Diphosphate Salt (CAS 1246815-14-4)
- Chloroquine Impurity 1 (CAS 133860-75-0)
- Chloroquine Phosphate (CAS 1446-17-9)
- Chloroquine Diphosphate Hydrate (CAS 29791-25-1)
- Chloroquine Dihydrochloride (CAS 3545-67-3)
- Chloroquine-d5 Diphosphate (CAS 50-63-5 (unlabelled))
- Chloroquine (CAS 54-05-7)
- Chloroquine Phosphate EP Impurity D (Chloroquine USP Related Compound G (Free Form)) (CAS 68121-48-2)
Recommended Standards
- 4-Cyclopropyltetrahydro-2H-pyran-4-ol (CAS 1416439-69-4)
- 3-Cyclopropoxy-4-(trifluoromethyl)picolinonitrile (CAS 1243405-27-7)
- 2-Chloro-1-fluoro-4-(methoxymethoxy)benzene (CAS 1862927-59-0)
- Cefoperazone Impurity 24 (CAS CATO-C4X-114924)
- Methyl 3-(4-{[(tert-butoxy)carbonyl]amino}phenyl)propanoate (CAS 318510-90-6)
- 3-Chloro-2,2-bis(chloromethyl)propan-1-ol (CAS 813-99-0)
- 4-chloro-2-(1H-pyrrole-2-carbonyl)aniline (CAS 74978-28-2)
- 3-(Chloromethyl)-7-(trifluoromethyl)quinoline (CAS 1610696-38-2)
- 2-Amino-1-methyl-4,5-dihydro-1H-imidazole-5-carboxylic acid (CAS 76146-25-3)
- Semaglutide impurity 256 (CAS CATO-C4X-2226256)
Why CATO?
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