(3-Bromo-6-chloro-2-fluorophenyl)boronic acid CAS 1451393-00-2
| CAS No. | 1451393-00-2 |
| Molecular Formula | C6H4BBrClFO2 |
| Molecular Weight | 253.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (3-Bromo-6-chloro-2-fluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
(3-Bromo-6-chloro-2-fluorophenyl)boronic acid (CAS 1451393-00-2) is a high-purity analytical reference standard with the molecular formula C6H4BBrClFO2 and a molecular weight of 253.26 g/mol.
The molecular framework of (3-Bromo-6-chloro-2-fluorophenyl)boronic acid (C6H4BBrClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (3-Bromo-6-chloro-2-fluorophenyl)boronic acid under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H4BBrClFO2 |
| Molecular Weight | 253.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F/Cl/Br-containing |
Related Bromo Standards
- (2-Bromo-3-chloro-6-fluorophenyl)boronic acid (CAS 1451392-82-7)
- (6-Bromo-3-chloro-2-fluorophenyl)boronic acid (CAS 1451392-87-2)
- (3-Bromo-2-chloro-6-fluorophenyl)boronic acid (CAS 1451393-16-0)
- (5-Bromo-3-chloro-2-fluorophenyl)boronic acid (CAS 1451393-27-3)
- (3-Bromo-2-chloro-5-fluorophenyl)boronic acid (CAS 2379538-57-3)
- 3-Bromo-4-chloro-2-fluorophenylboronic acid (CAS 1987879-74-2)
- 3-Bromo-5-chloro-2-fluorophenylboronic acid (CAS 2377608-61-0)
- 3-Bromo-5-chloro-4-fluorophenylboronic acid (CAS 2377608-50-7)
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