(3-Bromo-2-chloro-5-fluorophenyl)boronic acid CAS 2379538-57-3

Purity 97%+In StockPharmaceutical Standards
CAS No.2379538-57-3
Molecular FormulaC6H4BBrClFO2
Molecular Weight253.26 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(3-Bromo-2-chloro-5-fluorophenyl)boronic acid CAS 2379538-57-3 chemical structure

Description

The occurrence of (3-Bromo-2-chloro-5-fluorophenyl)boronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies (3-Bromo-2-chloro-5-fluorophenyl)boronic acid (CAS 2379538-57-3), a certified reference material (molecular formula C6H4BBrClFO2, MW 253.26 g/mol) for analytical method development and quality control.

The molecular framework of (3-Bromo-2-chloro-5-fluorophenyl)boronic acid (C6H4BBrClFO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine/bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (3-Bromo-2-chloro-5-fluorophenyl)boronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC6H4BBrClFO2
Molecular Weight253.26 g/mol
Purity97%+
StorageStore at room temperature, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)3.5
UV AbsorptionUV-absorbing
CAS Registry Year (est.)1999
Halogen ContentF/Cl/Br-containing

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