Cabazitaxel Impurity 22 CAS 146924-92-7
| CAS No. | 146924-92-7 |
| Molecular Formula | C9H9NO2 |
| Molecular Weight | 163.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 163.17 g/mol gives Cabazitaxel Impurity 22 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies Cabazitaxel Impurity 22 (CAS 146924-92-7), a pharmacopoeial impurity reference standard (molecular formula C9H9NO2, MW 163.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Cabazitaxel Impurity 22 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 163.17 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Cabazitaxel Impurity 22 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C9H9NO2 |
| Molecular Weight | 163.17 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Nitrogen Atoms | 1 |
Related Cabazitaxel Standards
- Cabazitaxel Impurity 60 (CAS 777885-04-8)
- Cabazitaxel Impurity 21 (CAS 132127-34-5)
- Cabazitaxel Impurity 26 (CAS 144790-01-2)
- Cabazitaxel Impurity 24 ( (2R,3S)-3-Amino-2-hydroxy-3-phenylpropionic Acid Ethyl Ester) (CAS 143615-00-3)
- Cabazitaxel Impurity 17 (CAS 160535-69-3)
- Cabazitaxel Impurity 37 (CAS 131023-37-5)
- Cabazitaxel Impurity 11 (CAS CATO-C4X-111511)
- Cabazitaxel Impurity 7 (CAS 1426815-65-7)
Recommended Standards
- Aripiprazole EP Impurity A (CAS 22246-18-0)
- Ezetimibe Impurity 52 (CAS 90319-52-1)
- Brexpiprazole Impurity 89 (CAS 15450-69-8)
- Ezetimibe Impurity 34 (CAS 99395-88-7)
- Pitolisant impurity 24 (CAS CATO-C4X-252024)
- Mianserin Impurity 50 (CAS CATO-C4X-136950)
- Nebivolol Impurity 66 (CAS 1017878-67-9)
- Ethyl 2-(3-formyl-4-nitrophenoxy)acetate (CAS 105728-02-7)
- 1-Benzyl-2,3-O-isopropylidene Glycerol (CAS 15028-56-5)
- Gadobutrol Impurity 187 (CAS CATO-C4X-2120187)
- 1-Benzyl-2-bromo-1H-imidazole (CAS 235426-32-1)
- 2,6-Dimethyl-4-nitrobenzoic acid (CAS 90564-17-3)
- 4-(Benzyloxy)-1,2-dichlorobenzene (CAS 1092840-89-5)
- Hexapeptide-9 (CAS 885024-94-2)
Why CATO?
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