Tolvaptan CAS 150683-30-0
| CAS No. | 150683-30-0 |
| Molecular Formula | C26H25ClN2O3 |
| Molecular Weight | 448.94 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Tolvaptan.
Tolvaptan (CAS 150683-30-0), molecular formula C26H25ClN2O3 and molecular weight 448.94 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C26H25ClN2O3, Tolvaptan contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 448.94 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C26H25ClN2O3 |
| Molecular Weight | 448.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- (R)-Tolvaptan (CAS 331947-66-1)
- (S)-Tolvaptan (CAS 331947-44-5)
- Tolvaptan Impurity 111 (CAS CATO-C4X-1955111)
- Tolvaptan Impurity 26 (CAS 1580889-25-3)
- Tolvaptan Impurity 69 (CAS 1580889-27-5)
- Tolvaptan Impurity 14 (CAS 137973-76-3)
- Tolvaptan Impurity 67 (CAS 1580889-26-4)
- Tolvaptan Impurity 68 (CAS 1580889-24-2)
Recommended Standards
- Azd3463 (CAS 1356962-20-3)
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Why CATO?
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