Tolvaptan Impurity 47 CAS 150683-52-6
| CAS No. | 150683-52-6 |
| Molecular Formula | C27H27ClN2O3 |
| Molecular Weight | 462.97 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution, Tolvaptan Impurity 47 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 462.97 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Tolvaptan Impurity 47 (CAS 150683-52-6) is a certified pharmaceutical impurity reference standard with the molecular formula C27H27ClN2O3 and a molecular weight of 462.97 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tolvaptan Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H27ClN2O3 |
| Molecular Weight | 462.97 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Tolvaptan Standards
- Tolvaptan Impurity 116 (CAS 1580889-35-5)
- Tolvaptan Impurity 126 (CAS CATO-C4X-1955126)
- Tolvaptan Impurity 65 (CAS CATO-C4X-195565)
- Tolvaptan Impurity 46 (CAS 2468638-31-3)
- Tolvaptan Impurity 96 (CAS 1587638-01-4)
- Tolvaptan Impurity 51 (CAS CATO-C4X-195551)
- Tolvaptan-d7 (CAS 1246818-18-7)
- Tolvaptan Impurity 108 (CAS CATO-C4X-1955108)
Recommended Standards
- Cetirizine Impurity 18 (CAS CATO-C4X-158218)
- 2-((5-(2-Chlorophenyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)-N-mesitylacetamide (CAS 335402-73-8)
- Levocetirizine Impurity 64 (CAS CATO-C4X-108364)
- 2-((5-(4-Chlorophenyl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)-N-(2,4-dimethylphenyl)acetamide (CAS 332947-78-1)
- Agomelatine Impurity 46 (CAS 1607465-50-8)
- Dapagliflozin Impurity 157 (CAS CATO-C4X-1138157)
- Flunarizine Impurity 10 (CAS 345-92-6)
- Bumetanide Impurity 105 (CAS CATO-C4X-1986105)
- 2-Oxo-2,3-dihydro-1H-imidazole-4,5-dicarboxamide (CAS 860260-25-9)
- 2-[3-(aminomethyl)phenoxy]-N-ethylacetamide hydrochloride (CAS 1375473-35-0)
- 206986-90-5 Citric acid trisilver salt hydrate Silver citrate hydrate (CAS 206986-90-5)
- Sabinyl acetate (CAS 3536-54-7)
- Europium(III) sodium 2,2',2'',2'''-(((4'-(4'-amino-[1,1'-biphenyl]-4-yl)-[2,2':6',2''-terpyridine]-6,6''-diyl)bis(methylene))bis(azanetriyl))tetraacetate (CAS 601494-52-4)
- Tirzepatide Impurity 58 (CAS CATO-C4X-324058)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com