Sertraline Impurity N1 CAS 152448-80-1
| CAS No. | 152448-80-1 |
| Molecular Formula | C16H12Cl2O |
| Molecular Weight | 291.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Sertraline Impurity N1 (CAS 152448-80-1), a pharmacopoeial impurity reference standard (molecular formula C16H12Cl2O, MW 291.17 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C16H12Cl2O, Sertraline Impurity N1 contains a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 291.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2O |
| Molecular Weight | 291.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Halogen Content | Cl-containing |
Related Sertraline Standards
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
- rac-Sertraline EP Impurity F (CAS 79560-19-3)
- Sertraline EP Impurity F (CAS 155748-61-1)
- Sertraline RC 6 (Base) (CAS 755752-66-0)
- Sertraline Impurity 1 (CAS 866018-46-4)
- Sertraline Impurity 66 (CAS CATO-C4X-134466)
- Sertraline Impurity 68 (CAS CATO-C4X-134468)
- Sertraline Impurity 72 (CAS CATO-C4X-134472)
Recommended Standards
- Ethyl 5-(2,6-dichlorophenoxy)pentanoate (CAS 1443345-15-0)
- 2,2-Dichloro-3,3-diethoxy-1-phenylpropan-1-one (CAS 160663-36-5)
- Ethyl 5-(2,3-dichlorophenoxy)pentanoate (CAS 1443337-92-5)
- (2E)-1-(3,4-Dichlorophenyl)-3-(4-methylphenyl)prop-2-en-1-one (CAS 168208-80-8)
- Trimebutine Impurity 20 (CAS CATO-C4X-185820)
- Apalutamide Impurity 105 (CAS CATO-C4X-2749105)
- Sacubitril impurity 9 (CAS CATO-C4X-28099)
- N-(3,4-difluorophenyl)-3-methoxythiophene-2-carboxamide (CAS 344273-43-4)
- 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS 21889-89-4)
- 5,6,7,8-Tetrahydroimidazo[1,2-a]pyridin-8-ol (CAS 156817-68-4)
- 1-(4-(4-Fluorobenzamido)benzyl)-N-phenyl-1H-imidazole-4-carboxamide (CAS 1251572-62-9)
- (5-Chloro-2-methylphenyl)methanamine (CAS 27917-13-1)
- 3-Hydroxy-4-(naphthalen-1-yloxy)butanimidamide hydrochloride (CAS 35991-90-3)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com