rac-Sertraline EP Impurity F CAS 79560-19-3
| CAS No. | 79560-19-3 |
| Molecular Formula | C16H12Cl2O |
| Molecular Weight | 291.17 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including rac-Sertraline EP Impurity F.
As a process- or degradation-related impurity, rac-Sertraline EP Impurity F (CAS 79560-19-3, C16H12Cl2O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C16H12Cl2O, rac-Sertraline EP Impurity F contains a hydroxyl group, an ether linkage, chlorine substitution, a polycyclic aromatic system; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 291.17 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures rac-Sertraline EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2O |
| Molecular Weight | 291.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1979 |
| Halogen Content | Cl-containing |
Related rac Standards
- Sertraline EP Impurity F Enantiomer (CAS 124379-29-9)
- Sertraline Impurity N1 (CAS 152448-80-1)
- Sertraline EP Impurity F (CAS 155748-61-1)
- Sertraline RC 6 (Base) (CAS 755752-66-0)
- Sertraline Impurity 1 (CAS 866018-46-4)
- Sertraline Impurity 66 (CAS CATO-C4X-134466)
- Sertraline Impurity 68 (CAS CATO-C4X-134468)
- Sertraline Impurity 72 (CAS CATO-C4X-134472)
Recommended Standards
- N-(4-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)cyclopropanamine (CAS 2096338-43-9)
- Methyl 2-(3,5-dichlorophenoxy)-4-methylpentanoate (CAS 2044706-76-3)
- 2-bromo-1-(4-acetylpiperazin-1-yl)-3-methylbutan-1-one (CAS 1016752-51-4)
- Ethyl 5-(2,4-dichlorophenoxy)pentanoate (CAS 91820-58-5)
- Pregabalin impurity 92 (CAS CATO-C4X-131292)
- Vonoprazan Fumarate Impurity 81 (CAS CATO-C4X-102081)
- Famotidine Impurity 84 (CAS CATO-C4X-139284)
- 2-Hydrazinyl-4-(2-(trifluoromethyl)phenyl)thiazole (CAS 900021-14-9)
- 4-Chloro-2-cyclopropyl-5-iodo-6-methylpyrimidine (CAS 1517863-66-9)
- 4-Methylpiperidin-3-one hydrochloride (CAS 1408076-42-5)
- Butyl 3-sulfamoylpropanoate (CAS 1183230-82-1)
- 2-(4-Aminophenyl)-1H-indole-3-carbaldehyde (CAS 918482-42-5)
- Dinonyl Phenol (CAS 1323-65-5)
- C-Peptide 1 (rat) (CAS 41475-27-8)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com