Flurbiprofen Impurity 140 CAS 1531637-33-8

Purity 97%+In StockPharmacopoeial Impurity Standards
CAS No.1531637-33-8
Molecular FormulaC18H10F4
Molecular Weight302.27 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Flurbiprofen Impurity 140 CAS 1531637-33-8 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 302.27 g/mol gives Flurbiprofen Impurity 140 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies Flurbiprofen Impurity 140 (CAS 1531637-33-8), a pharmacopoeial impurity reference standard (molecular formula C18H10F4, MW 302.27 g/mol) used for the identification and quantification of trace impurities in APIs.

Structurally, Flurbiprofen Impurity 140 (C18H10F4) contains fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 302.27 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H10F4
Molecular Weight302.27 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)12.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1992
Halogen ContentF-containing

Related Flurbiprofen Standards

Recommended Standards

Why CATO?