Flurbiprofen Impurity 153 CAS CATO-C4X-1444153
| CAS No. | CATO-C4X-1444153 |
| Molecular Formula | C14H18FNO5 |
| Molecular Weight | 299.29 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 299.29 g/mol gives Flurbiprofen Impurity 153 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Flurbiprofen Impurity 153 (CAS CATO-C4X-1444153) is a certified pharmaceutical impurity reference standard with the molecular formula C14H18FNO5 and a molecular weight of 299.29 g/mol.
Structurally, Flurbiprofen Impurity 153 (C14H18FNO5) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 6.0, corresponding to approximately 6 ring(s) or double-bond equivalent(s). With a molecular weight of 299.29 g/mol, it falls into the medium-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H18FNO5 |
| Molecular Weight | 299.29 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Flurbiprofen Standards
- Flurbiprofen Impurity 170 (CAS 945721-92-6)
- Flurbiprofen Impurity 93 (CAS CATO-C4X-144493)
- Flurbiprofen Impurity 138 (CAS 88975-22-8)
- Flurbiprofen Impurity 78 (CAS CATO-C4X-144478)
- Flurbiprofen Impurity 141 (CAS 486455-73-6)
- Flurbiprofen Impurity 140 (CAS 1531637-33-8)
- Flurbiprofen Impurity 129 (CAS 61467-16-1)
- Flurbiprofen Impurity 13 (CAS CATO-C4X-144413)
Recommended Standards
- 436093-06-0 2-[5-(2-Aminophenyl)-2H-tetrazol-2-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide DTXSID30357670 (CAS 436093-06-0)
- Baricitinib Impurity 110 (CAS CATO-C4X-2260110)
- 436092-90-9 2-[5-(4-Aminophenyl)-2H-tetrazol-2-yl]-N-(5-methyl-1,2-oxazol-3-yl)acetamide DTXSID20357664 (CAS 436092-90-9)
- 【禁售不询】SAXITOXIN (CAS 35523-89-8)
- Voglibose Impurity 8 (CAS CATO-C4X-17808)
- Gadobutrol Impurity 3 (CAS 1822607-61-3)
- Lifitegrast Impurity 129 (CAS 2605229-68-1)
- 2-{3-[(4-tert-butylphenoxy)methyl]phenyl}-1,3-benzothiazole (CAS 866136-12-1)
- 4-((Pyridin-3-ylmethyl)amino)benzoic acid (CAS 5966-19-8)
- 54526-95-3 C23H32O5 (CAS 54526-95-3)
- (S)-1-Cyclobutyl-2-methylpiperazine Dihydrochloride (CAS 1227610-42-5)
- 4-Fluoro-3-nitrobenzotrifluoride (CAS 367-86-2)
- Methyl 3-(4-bromophenyl)-3-(1H-pyrrol-1-yl)propanoate (CAS 439094-24-3)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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