Entacapone Impurity 21 CAS 158693-04-0
| CAS No. | 158693-04-0 |
| Molecular Formula | C15H17N3O5 |
| Molecular Weight | 319.31 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Entacapone Impurity 21 (CAS 158693-04-0) is a certified pharmaceutical impurity reference standard with the molecular formula C15H17N3O5 and a molecular weight of 319.31 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Entacapone Impurity 21 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 319.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Entacapone Impurity 21 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H17N3O5 |
| Molecular Weight | 319.31 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2002 |
| Nitrogen Atoms | 3 |
Related Entacapone Standards
- Entacapone Impurity 22 (CAS 857629-78-8)
- Entacapone Impurity 9 (CAS 146698-91-1)
- Entacapone impurity 19 (CAS CATO-C4X-162919)
- Entacapone Impurity 56 (CAS CATO-C4X-162956)
- Entacapone EP Impurity H (CAS 1150310-15-8)
- Entacapone Impurity 23 (CAS 1185241-19-3)
- Entacapone Impurity 11 (CAS CATO-C4X-162911)
- Entacapone Impurity 10 (CAS CATO-C4X-162910)
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- Pancreatic Polypeptide (31-36), amide, human (CAS 74012-13-8)
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