Empagliflozin Impurity 14 CAS 1620758-34-0
| CAS No. | 1620758-34-0 |
| Molecular Formula | C23H29ClO8 |
| Molecular Weight | 468.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin Impurity 14 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Empagliflozin Impurity 14 (CAS 1620758-34-0) is a certified pharmaceutical impurity reference standard with the molecular formula C23H29ClO8 and a molecular weight of 468.92 g/mol.
Empagliflozin Impurity 14 (C23H29ClO8) contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29ClO8 |
| Molecular Weight | 468.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 110 (CAS CATO-C4X-1065110)
- Empagliflozin Impurity 12 (CAS 1620758-34-0 & 2452301-18-5)
- Empagliflozin Impuirity 141 (CAS CATO-C4X-1065141)
- Empagliflozin Impurity 17 (CAS CATO-C4X-106517)
- Empagliflozin impurity 241 (CAS CATO-C4X-1065241)
- Empagliflozin Impurity 278 (CAS CATO-C4X-1065278)
- Empagliflozin Impurity 86 (CAS CATO-C4X-1065286)
- Empagliflozin Impurity 314 (CAS CATO-C4X-1065314)
Recommended Standards
- Ertugliflozin impurity 01 (CAS 1528636-39-6)
- Olaparib Impurity 49 (CAS CATO-C4X-113549)
- Ethyl (1-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2,3-dihydro-1H-inden-2-yl)carbamate (CAS 303152-95-6)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(E)-2-[(4-methoxyphenyl)amino]ethenyl]-1,2-thiazole-4-carbonitrile (CAS 338412-95-6)
- Tofacitinib Impurity 76 (CAS CATO-C4X-107976)
- Benserazide Impurity 55 (CAS CATO-C4X-142755)
- Norfloxacin Impurity 21 (CAS 103240-27-3)
- Niraparib Impurity 42 (CAS 1476776-92-7)
- Ethyl isonicotinimidate (CAS 41050-96-8)
- 3-(1,3-Benzodioxol-5-yl)-1,2,4-oxadiazol-5-ol (CAS 931358-03-1)
- 5-(4-Chloro-3-nitrophenyl)-1,3,4-thiadiazol-2-amine (CAS 109702-87-6)
- 2-(Isopentylamino)-5-nitrobenzonitrile (CAS 945299-76-3)
- 6-methoxy-2-azaspiro[3.3]heptane;hydrochloride (CAS 1638761-19-9)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
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