Empagliflozin Impuirity 141 CAS CATO-C4X-1065141
| CAS No. | CATO-C4X-1065141 |
| Molecular Formula | C23H29ClO8 |
| Molecular Weight | 468.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Empagliflozin Impuirity 141 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Empagliflozin Impuirity 141 (CAS CATO-C4X-1065141) is a certified pharmaceutical impurity reference standard with the molecular formula C23H29ClO8 and a molecular weight of 468.92 g/mol.
The molecular framework of Empagliflozin Impuirity 141 (C23H29ClO8) is characterized by a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C23H29ClO8 |
| Molecular Weight | 468.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Empagliflozin Standards
- Empagliflozin Impurity 110 (CAS CATO-C4X-1065110)
- Empagliflozin Impurity 12 (CAS 1620758-34-0 & 2452301-18-5)
- Empagliflozin Impurity 14 (CAS 1620758-34-0)
- Empagliflozin Impurity 17 (CAS CATO-C4X-106517)
- Empagliflozin impurity 241 (CAS CATO-C4X-1065241)
- Empagliflozin Impurity 278 (CAS CATO-C4X-1065278)
- Empagliflozin Impurity 86 (CAS CATO-C4X-1065286)
- Empagliflozin Impurity 314 (CAS CATO-C4X-1065314)
Recommended Standards
- Ertugliflozin impurity 01 (CAS 1528636-39-6)
- Olaparib Impurity 49 (CAS CATO-C4X-113549)
- Ethyl (1-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)-2,3-dihydro-1H-inden-2-yl)carbamate (CAS 303152-95-6)
- Dapagliflozin Impurity 84 (CAS CATO-C4X-113884)
- Roxatidine Impurity 60 (CAS CATO-C4X-121360)
- Sunitinib Impurity 21 (CAS CATO-C4X-133321)
- Benzhexol Impurity 5 (CAS 67562-42-9)
- JNJ 10191584 Maleate (CAS 869497-75-6)
- (R)-2-(2,6-dichlorophenyl)pyrrolidine (CAS 1241679-41-3)
- Tert-butyl (3,5-dimethylphenyl)carbamate (CAS 203321-89-5)
- N-(4-(1,1-Dioxidoisothiazolidin-2-yl)phenyl)thiophene-2-carboxamide (CAS 900005-16-5)
- 3-(1H-pyrrol-3-yl)prop-2-enoic acid (CAS 856597-79-0)
- 3-{1-[(1-methyl-1h-imidazol-2-yl)sulfanyl]ethyl}aniline (CAS 1247635-33-1)
- Semaglutide impurity 80 (CAS CATO-C4X-222680)
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