Cabozantinib-d4 CAS 1802168-53-1
| CAS No. | 1802168-53-1 |
| Molecular Formula | - |
| Molecular Weight | 505.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabozantinib-d4.
Cabozantinib-d4 (CAS 1802168-53-1) is a high-purity analytical reference standard with the molecular formula C28H20D4FN3O5 and a molecular weight of 505.53 g/mol.
Cabozantinib-d4 (C28H20D4FN3O5) contains deuterium isotope labeling, a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Cabozantinib-d4 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H20D4FN3O5 |
| Molecular Weight | 505.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 20.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Cabozantinib Standards
- Cabozantinib-d6 (CAS 1802168-46-2)
- Cabozantinib (CAS 849217-68-1)
- Cabozantinib Impurity 17 (CAS CATO-C4X-201817)
- Cabozantinib Impurity N1 (CAS 1628530-38-0)
- Cabozantinib Impurity 36 (CAS 1628530-41-5)
- Cabozantinib N-oxide (CAS 1621681-63-7)
- Cabozantinib Impurity 13 (CAS 849221-94-9)
- Cabozantinib Impurity 45 (CAS CATO-C4X-201845)
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- Dabrafenib Impurity N1 (CAS 1195765-47-9)
- N-(1,5-Dimethyl-1,4,5,6-tetrahydro-1,3,5-triazin-2-yl)nitramide (CAS 136516-16-0)
- 4-Chloro-7-methyl-2-(pyridin-4-yl)indoline (CAS 594820-96-9)
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- 2,6-Difluoro-4-methoxyphenylboronic acid (CAS 406482-20-0)
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- Methyl 2-amino-2-(2-methylpyrrolo[2,1-f][1,2,4]triazin-7-yl)acetate (CAS 2089664-13-9)
- 2-((2-(Methoxycarbonyl)phenyl)amino)-2-oxoethyl 5-methylthiophene-2-carboxylate (CAS 721913-39-9)
- Quercetin-7-O-β-D-glucopyranoside (CAS 491-50-9)
- 2,2,2-Trifluoroethyl 2-(4-methylpiperazin-1-yl)ethane-1-sulfonate dioxalate (CAS 353744-64-6)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com