Metoprolol EP Impurity J CAS 163685-37-8
| CAS No. | 163685-37-8 |
| Molecular Formula | C18H31NO5 |
| Molecular Weight | 341.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C18H31NO5, Metoprolol EP Impurity J contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 341.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO supplies Metoprolol EP Impurity J (CAS 163685-37-8), a pharmacopoeial impurity reference standard (molecular formula C18H31NO5, MW 341.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Metoprolol EP Impurity J meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H31NO5 |
| Molecular Weight | 341.44 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Nitrogen Atoms | 1 |
Related Metoprolol Standards
- Metoprolol Impurity 19 (CAS 230975-30-1)
- Metoprolol Impurity 52 (CAS CATO-C4X-136752)
- Metoprolol Impurity 33 (CAS CATO-C4X-136733)
- Metoprolol Impurity 34 (CAS CATO-C4X-136734)
- Metoprolol Impurity 35 (CAS CATO-C4X-136735)
- Metoprolol Impurity 46 (CAS CATO-C4X-136746)
- Metoprolol Impurity 49 (CAS CATO-C4X-136749)
- Metoprolol Impurity 48 (CAS CATO-C4X-136748)
Recommended Standards
- Propafenone Impurity 27 (CAS CATO-C4X-132227)
- 3-Chloro-2,6-dibromo-4-methylphenyl isothiocyanate (CAS 1000572-53-1)
- Propafenone Impurity 3 (CAS CATO-C4X-132219)
- 3-Chloro-4,6-dibromo-2-methylphenyl isothiocyanate (CAS 1000573-77-2)
- Tirofiban Impurity 33 (CAS 16870-43-2)
- Gefitinib Impurity 40 (CAS 179688-53-0)
- Cefotaxime Impurity 27 (CAS CATO-C4X-120127)
- 4-ethylmorpholine-2-carbonitrile (CAS 1354950-43-8)
- 5-Chloro-2-hydroxy-4-isobutoxybenzonitrile (CAS 1361003-66-8)
- Methyl 3-(2-chloro-4-methylphenyl)-5-nitrobenzoate (CAS 1820614-02-5)
- Methyl 5-bromo-2-(methylsulfonamido)benzoate (CAS 452350-33-3)
- 4-(4-Methylphenyl)-5-(pyrrolidin-1-yl)-4h-1,2,4-triazole-3-thiol (CAS 812648-27-4)
- 2-Propenoic acid, 2-methyl-, polymer with ethenylbenzene, 2-ethylhexyl 2-propenoate and 2-propenenitrile (CAS 26873-77-8)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com