Apixaban Impurity 26 CAS 1643330-62-4
| CAS No. | 1643330-62-4 |
| Molecular Formula | C20H26ClN3O3 |
| Molecular Weight | 391.89 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Apixaban Impurity 26 (CAS 1643330-62-4) is a certified pharmaceutical impurity reference standard with the molecular formula C20H26ClN3O3 and a molecular weight of 391.89 g/mol.
Based on its molecular formula C20H26ClN3O3, Apixaban Impurity 26 contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 391.89 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Apixaban Impurity 26 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H26ClN3O3 |
| Molecular Weight | 391.89 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1993 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Apixaban Standards
- Apixaban Impurity 63 (CAS 1466571-07-2)
- Apixaban Impurity 103 (CAS CATO-C4X-1088103)
- Apixaban Impurity 145 (CAS CATO-C4X-1088145)
- Apixaban Impurity 83 (CAS CATO-C4X-108883)
- Apixaban impurity 158 (CAS 148476-97-5)
- Apixaban Impurity 50 (CAS CATO-C4X-108850)
- Apixaban Impurity 52 (CAS CATO-C4X-108852)
- Apixaban Impurity 140 (CAS CATO-C4X-1088140)
Recommended Standards
- tert-Butyl (S)-4-(1-(7-chloro-1,6-naphthyridin-2-yl)-1-hydroxyethyl)piperidine-1-carboxylate (CAS 2750239-71-3)
- 9-Benzyl-N-(4-butylphenyl)-2-chloro-9H-purin-6-amine (CAS 125802-44-0)
- tert-Butyl (R)-4-(1-(7-chloro-1,6-naphthyridin-2-yl)-1-hydroxyethyl)piperidine-1-carboxylate (CAS 2639543-22-7)
- (2-Chloropyridin-3-yl)bis(2-(methylthio)pyrimidin-4-yl)methanol (CAS 330823-21-7)
- Rimegepant Impurity 106 (CAS CATO-C4X-2487106)
- Pramipexole Impurity 60 (CAS 687639-03-8)
- Ebastine Impurity 19 (CAS CATO-C4X-202919)
- Thiamphenicol (CAS 847-25-6)
- 1196723-95-1 HSF1B (CAS 1196723-95-1)
- 2-Isobutyl-1-oxo-1,2-dihydroisoquinoline-4-carbohydrazide (CAS 1170238-16-0)
- 2-(3,4,5-Trihydroxyphenyl)chromen-4-one (CAS 126432-36-8)
- 3a,4,5,6,7,7a-Hexahydro-4,7-methano-1H-inden-6-ol (CAS 3385-61-3)
- 2-(2-Azabicyclo[2.1.1]hexan-1-yl)acetic acid hydrochloride (CAS 637740-18-2)
- Insulin Degludec Impurity 9 (CAS CATO-C4X-21579)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com