Abemaciclib Impurity 145 CAS CATO-C4X-2937145
| CAS No. | CATO-C4X-2937145 |
| Molecular Formula | C23H34N6O |
| Molecular Weight | 410.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Abemaciclib Impurity 145 (CAS CATO-C4X-2937145) is a certified pharmaceutical impurity reference standard with the molecular formula C23H34N6O and a molecular weight of 410.56 g/mol.
Based on its molecular formula C23H34N6O, Abemaciclib Impurity 145 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 410.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Abemaciclib Impurity 145 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H34N6O |
| Molecular Weight | 410.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Abemaciclib Standards
- Abemaciclib Impurity 13 (CAS 1648707-16-7)
- Abemaciclib Impurity 54 (CAS CATO-C4X-293754)
- Abemaciclib Impurity 12 (CAS 1627082-92-1)
- Abemaciclib Impurity 92 (CAS CATO-C4X-293792)
- Abemaciclib Impurity 57 (CAS CATO-C4X-293757)
- Abemaciclib Impurity 161 (CAS CATO-C4X-2937161)
- Abemaciclib Impurity 10 (CAS CATO-C4X-293710)
- Abemaciclib Impurity 34 (CAS CATO-C4X-293734)
Recommended Standards
- N-(4-(4-Methoxyphenyl)thiazol-2-yl)-2-((3-(methylthio)-1,2,4-thiadiazol-5-yl)thio)acetamide (CAS 876880-53-4)
- 10-((2-Azidoethyl)(methyl)amino)decyl 4-methylbenzenesulfonate (CAS 2763904-55-6)
- Trichlophenidin (CAS 53720-80-2)
- 1'-Cyclohexyl-2,4',5,5'-tetramethyl-3'-(phenylsulfonyl)-1'H-1,2'-bipyrrole (CAS 860648-62-0)
- Indometacin Impurity 19 (CAS CATO-C4X-147019)
- Carbocisteine Impurity 55 (CAS CATO-C4X-201055)
- Alogliptin impurity 76 (CAS 1353254-17-7（free base）)
- [6-(methylsulfanyl)pyridin-3-yl]boronic acid (CAS 321438-86-2)
- 3-(4-(Methylsulfonyl)piperazin-1-yl)-3-oxopropanenitrile (CAS 1492720-09-8)
- L-Sorbose-6- (CAS 478506-38-6)
- Methyl 3-[2-(dimethylsulfamoyl)phenyl]-5-fluorobenzoate (CAS 1820734-79-9)
- 6-Bromo-7-ethoxy-3,4-dihydroquinolin-2(1H)-one (CAS 1392223-87-8)
- Ethyl 2-chloro-4-(cyclopropylamino)pyrimidine-5-carboxylate (CAS 1192711-36-6)
- Mast Cell Degranulating Peptide HR-1 (CAS 80533-94-4)
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