Ketoconazole Impurity 14 CAS 170210-49-8
| CAS No. | 170210-49-8 |
| Molecular Formula | C14H14Cl2N2O3 |
| Molecular Weight | 329.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ketoconazole Impurity 14.
CATO supplies Ketoconazole Impurity 14 (CAS 170210-49-8), a pharmacopoeial impurity reference standard (molecular formula C14H14Cl2N2O3, MW 329.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C14H14Cl2N2O3, Ketoconazole Impurity 14 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 329.18 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Ketoconazole Impurity 14 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H14Cl2N2O3 |
| Molecular Weight | 329.18 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2005 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Ketoconazole Standards
- Ketoconazole Impurity 10 (CAS 61441-65-4)
- Ketoconazole Impurity 11 (CAS 84682-23-5)
- Ketoconazole Impurity 13 (and enantiomer) (CAS 61397-58-8)
- Ketoconazole Impurity 35 (CAS CATO-C4X-147235)
- Ketoconazole Impurity N15 (CAS 170210-42-1)
- Ketoconazole Impurity 20 (CAS CATO-C4X-147220)
- Ketoconazole Impurity 19 (CAS CATO-C4X-147219)
- Ketoconazole impurity 31 (CAS CATO-C4X-147231)
Recommended Standards
- Prothiophos-Oxon (CAS 38527-91-2)
- Tadalafil Impurity 58 (CAS CATO-C4X-108758)
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- Butylphthalide Impurity 80 (CAS CATO-C4X-181380)
- Tiotropium Impurity 34 (CAS 169219-67-4)
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- 4-Methyl-2-(1-pyrrolidinyl)pentanoic Acid (CAS 937669-97-1)
- 7-Vinyl-1H-pyrazolo[3,4-c]pyridine (CAS 1374652-52-4)
- 3-(4-Methoxybenzyl)-4-methylpentanoic acid (CAS 1225766-70-0)
- 3-(Tert-Butyl)-5-(chloromethyl)-2-hydroxybenzaldehyde (CAS 183017-88-1)
- Neuropeptide GE (CAS 134748-04-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com