Tadalafil Impurity 74 CAS 171596-41-1
| CAS No. | 171596-41-1 |
| Molecular Formula | C20H18N2O4 |
| Molecular Weight | 350.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 350.37 g/mol gives Tadalafil Impurity 74 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Tadalafil Impurity 74 (CAS 171596-41-1, C20H18N2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Tadalafil Impurity 74 (C20H18N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Tadalafil Impurity 74 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18N2O4 |
| Molecular Weight | 350.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2006 |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil Impurity 133 (CAS 171596-44-4)
- Tadalafil Impurity 134 (CAS 171596-43-3)
- Tadalafil Impurity 15 (CAS 171596-42-2)
- Tadalafil Impurity 178 (CAS CATO-C4X-1087178)
- Tadalafil Impurity 36 (CAS CATO-C4X-108736)
- Tadalafil Impurity 83 (CAS CATO-C4X-108783)
- Tadalafil Impurity 21 (CAS 951661-85-1)
- Tadalafil Impurity 23 (CAS 951661-82-8)
Recommended Standards
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- (R)-1-(3-fluoro-4-(trifluoromethoxy)phenyl)but-3-en-1-amine (CAS 1272736-42-1)
- Methyl (S)-3-amino-5-phenylpentanoate hydrochloride (CAS 2086201-19-4)
- 4-Fluoro-3-(trifluoromethyl)-1,1'-biphenyl (CAS 1032506-93-6)
- Topiroxostat Impurity 50 (CAS CATO-C4X-105550)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com