Tadalafil Impurity 21 CAS 951661-85-1

Description

Compared with other compounds in its class, the molecular weight of 349.38 g/mol gives Tadalafil Impurity 21 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Tadalafil Impurity 21 (CAS 951661-85-1) is a certified pharmaceutical impurity reference standard with the molecular formula C20H19N3O3 and a molecular weight of 349.38 g/mol.

Based on its molecular formula C20H19N3O3, Tadalafil Impurity 21 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 349.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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