Tadalafil Impurity 36 CAS CATO-C4X-108736
| CAS No. | CATO-C4X-108736 |
| Molecular Formula | C20H18N2O4 |
| Molecular Weight | 350.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Tadalafil Impurity 36 (CAS CATO-C4X-108736), a pharmacopoeial impurity reference standard (molecular formula C20H18N2O4, MW 350.37 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of Tadalafil Impurity 36 (C20H18N2O4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Tadalafil Impurity 36 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18N2O4 |
| Molecular Weight | 350.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 2 |
Related Tadalafil Standards
- Tadalafil Impurity 133 (CAS 171596-44-4)
- Tadalafil Impurity 134 (CAS 171596-43-3)
- Tadalafil Impurity 15 (CAS 171596-42-2)
- Tadalafil Impurity 178 (CAS CATO-C4X-1087178)
- Tadalafil Impurity 74 (CAS 171596-41-1)
- Tadalafil Impurity 83 (CAS CATO-C4X-108783)
- Tadalafil Impurity 21 (CAS 951661-85-1)
- Tadalafil Impurity 23 (CAS 951661-82-8)
Recommended Standards
- Ilaprazole Impurity 86 (CAS CATO-C4X-113086)
- Nintedanib Impurity 128 (CAS CATO-C4X-1814128)
- Axitinib Impurity 71 (CAS CATO-C4X-107171)
- Baloxavir Marboxil Impurity 212 (CAS CATO-C4X-2108212)
- Trifarotene Impurity 1 (CAS 850012-53-2)
- Buserelin EP Impurity F (CAS CATO-C4X-22128)
- Ampicillin Impurity 92 (CAS CATO-C4X-144392)
- 9-(4-Carboxyphenyl)-9H-carbazole-3,6-dicarboxylic acid (CAS 1627605-99-5)
- Miproxifene (CAS 129612-87-9)
- 5-Iodo-1H-indazole-3-carbaldehyde (CAS 677702-22-6)
- (R)-2-(2-methyl-4-nitrophenyl)pyrrolidine (CAS 1213357-33-5)
- 2-(1-Amino-3-methylbutyl)pyrido[3,4-d]pyrimidin-4(3H)-one (CAS 1708250-60-5)
- (2E)-1-(4-Methylphenyl)-3-(thiophen-2-yl)prop-2-en-1-one (CAS 6028-89-3)
- Semaglutide impurity 32 (CAS CATO-C4X-222632)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com