Celecoxib Impurity 21 HCl CAS 17852-52-7
| CAS No. | 17852-52-7 |
| Molecular Formula | C6H9N3O2S |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Celecoxib Impurity 21 HCl (CAS 17852-52-7), a pharmacopoeial impurity reference standard (molecular formula C6H9N3O2SHCl, MW 223.68 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Celecoxib Impurity 21 HCl (C6H9N3O2SHCl) contains an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 3.0, corresponding to approximately 3 ring(s) or double-bond equivalent(s). With a molecular weight of 223.68 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Celecoxib Impurity 21 HCl under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2S HCl |
| Molecular Weight | 223.68 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1962 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
- Celecoxib Impurity 9 (CAS 1061214-06-9)
- Celecoxib Impurity 12 (CAS 1061214-09-2)
- Celecoxib Carboxylic Acid Methyl Ester (CAS 1189893-75-1)
- Celecoxib Impurity 38 (CAS 131774-72-6)
- Celecoxib Impurity 13 (CAS 1576-43-8)
- Celecoxib Impurity 22 (CAS 163266-02-2)
- Celecoxib (CAS 169590-42-5)
- Celecoxib Impurity 32 (CAS 170569-87-6)
Recommended Standards
- Tirzepatide Impurity 21 X TFA Salt (CAS CATO-C4X-324021)
- Palbociclib Impurity 183 (CAS CATO-C4X-1125183)
- Prusogliptin Impurity 8 (CAS CATO-C4X-32848)
- 6-Bromo-2,2-dimethyl-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-one (CAS 1196153-28-2)
- N,N-Dimethylnonylamine (CAS 17373-27-2)
- 4,4-Difluorospiro[2.2]pentane-1-carboxylic acid (CAS 2361635-28-9)
- Sacubitril impurity 54 (CAS 149709-63-7)
- 2-Amino-5-oxo-5,6,7,8-tetrahydro-4H-chromene-3,4,4-tricarbonitrile (CAS 30404-07-0)
- 2,3-Dimethoxyquinoxaline (CAS 6333-43-3)
- Semaglutide Impurity 18 (CAS 1671100-14-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com