Celecoxib Impurity 38 CAS 131774-72-6
| CAS No. | 131774-72-6 |
| Molecular Formula | C6H9N3O2S |
| Molecular Weight | 187.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, an aromatic ring system, Celecoxib Impurity 38 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 187.22 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Celecoxib Impurity 38 (CAS 131774-72-6, C6H9N3O2S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Celecoxib Impurity 38 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H9N3O2S |
| Molecular Weight | 187.22 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1994 |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Celecoxib Standards
Recommended Standards
- Vonoprazan Impurity 57 (CAS 2726830-13-1)
- 4-Hydroxymethylbenzenesulfonamide (CAS 67472-44-0)
- 5-Thiazolecarboxylicacid, 4,5-dihydro-2-methyl-4-oxo-, ethyl ester 89776-82-9 ACMC-1CUO1 (CAS 89776-82-9)
- Timolol EP Impurity D (CAS 30165-97-0)
- Phloroglucinol impurity 50 (CAS CATO-C4X-221750)
- Ilaprazole Impurity 73 (CAS 1378653-43-0)
- N-Nitroso Acarbose impurity 12 (CAS CATO-C4X-117312)
- N1-(3-ethoxypropyl)-N1-(furan-2-ylmethyl)propane-1,3-diamine (CAS 1119450-31-5)
- H-Gly-Gly-Tyr-Arg-OH TFA salt (CAS 70195-20-9(Free Base))
- N,N-diethyl-1-(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carbonyl)piperidine-3-carboxamide hydrochloride (CAS 1257856-45-3)
- 5-Chloro-N-(3-chlorophenyl)pyrazine-2-carboxamide (CAS 1438854-00-2)
- 3-Bromo-2-(bromomethyl)-1,1,1-trifluoropropane (CAS 1263377-32-7)
- 3-[(2-Bromoacetyl)amino]-N-methyl-N-phenylbenzamide (CAS 1138443-01-2)
- Tirzepatide Impurity 11 TFA salt (CAS CATO-C4X-324011)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com