Celecoxib Impurity 22 CAS 163266-02-2
| CAS No. | 163266-02-2 |
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Celecoxib Impurity 22 (CAS 163266-02-2), a pharmacopoeial impurity reference standard (molecular formula C11H9F3O2, MW 230.18 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system, Celecoxib Impurity 22 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 230.18 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Celecoxib Impurity 22 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C11H9F3O2 |
| Molecular Weight | 230.18 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2003 |
| Halogen Content | F-containing |
Related Celecoxib Standards
- Celecoxib Impurity 25 (CAS CATO-C4X-104325)
- Celecoxib Impurity 49 (CAS 720-94-5)
- Celecoxib Impurity 67 (CAS 910303-54-7)
- Celecoxib Impurity 57 (CAS CATO-C4X-104357)
- Celecoxib Impurity 59 (CAS CATO-C4X-104359)
- Celecoxib Impurity 11 (CAS 219986-64-8)
- Celecoxib Impurity 54 (CAS 948293-46-7)
- Celecoxib Impurity 1 (CAS 54779-81-6)
Recommended Standards
- (4-ethenylphenyl)methyl 2,2,2-tris(fluoranyl)ethanoate 2,2,2-trifluoroacetic acid (4-ethenylphenyl)methyl ester 229956-99-4 A816465 (CAS 229956-99-4)
- Methyl 4-[1-(trifluoromethyl)vinyl]benzoate (CAS 357274-86-3)
- methyl 3-[4-(trifluoromethyl)phenyl]prop-2-enoate (CAS 79947-88-9)
- Methyl 3-[1-(trifluoromethyl)vinyl]benzoate (CAS 893738-55-1)
- Leuprorelin Impurity 48 (CAS CATO-C4X-182248)
- Losartan Impurity 27 (CAS CATO-C4X-168327)
- Ethyl 3-oxo-2,4-diphenylbutanoate (CAS 2901-29-3)
- 2,4-Dimorpholinonitrobenzene (CAS 133387-34-5)
- CyclopentylmethanamineHCl (CAS 58714-85-5)
- PACAP-38 (6-38) (human, chicken, mouse, ovine, porcine, rat) trifluoroacetate salt (CAS 143748-18-9)
- 3-Amino-8-thiabicyclo[3.2.1]octane 8,8-dioxide hydrochloride (CAS 2126162-54-5)
- 3,4-Difluoro-5-hydroxybenzonitrile (CAS 186590-38-5)
- 2-Methylimidazo[1,2-a]pyridine-3,8-diol (CAS 769090-82-6)
- Neuropeptide Y (13-36) (human, rat) (CAS 122341-40-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com