Glumetinib Impurity 15 CAS CATO-C4X-325915
| CAS No. | CATO-C4X-325915 |
| Molecular Formula | C12H10Br2N4 |
| Molecular Weight | 370.04 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Glumetinib Impurity 15 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies Glumetinib Impurity 15 (CAS CATO-C4X-325915), a pharmacopoeial impurity reference standard (molecular formula C12H10Br2N4, MW 370.04 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, bromine substitution, Glumetinib Impurity 15 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 370.04 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C12H10Br2N4 |
| Molecular Weight | 370.04 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 4 |
Related Glumetinib Standards
- Glumetinib Impurity 5 (CAS CATO-C4X-32595)
- Glumetinib Impurity 6 (CAS CATO-C4X-32596)
- Glumetinib Impurity 7 (CAS CATO-C4X-32597)
- Glumetinib Impurity 4 (CAS CATO-C4X-32594)
- Glumetinib impurity 1 (CAS CATO-C4X-32591)
- Glumetinib Impurity 2 (CAS CATO-C4X-32592)
- Glumetinib Impurity 3 (CAS CATO-C4X-32593)
- Glumetinib (CAS 1642581-63-2)
Recommended Standards
- Telmisartan Impurity 22 (CAS 1797894-62-2)
- N-(4-bromo-3-iodophenyl)thietan-3-amine (CAS 1865113-94-5)
- Ambroxol Impurity 82 (CAS CATO-C4X-108582)
- 1,1,1,2,2,3,3,4,4,5,5,6,6,7,7-Pentadecafluoroheptane (CAS 27213-61-2)
- Abemaciclib Impurity 26 (CAS CATO-C4X-293726)
- Butylphthalide Impurity 82 (CAS CATO-C4X-181382)
- Vonoprazan Impurity 275 (CAS CATO-C4X-1020275)
- n-Isopropyl-4-(trifluoromethoxy)aniline (CAS 174181-16-9)
- 2-(2-Chlorobenzyl)-DL-alanine (CAS 21158-71-4)
- 3-(2-Cyanopropan-2-yl)benzonitrile (CAS 1314647-07-8)
- 7-Ethyl-10-(4-[[benzylcarbamoyl]amino]-1-piperidino)carbonyloxycamptothecin (CAS 1217686-49-1)
- (4-Hydroxy-3-methoxyphenyl)dimethylphosphine oxide (CAS 2903923-63-5)
- 5,6,7-Trimethyl-2-[(2-methylpropyl)sulfanyl]-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 442672-66-4)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
Why CATO?
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