Abemaciclib-d5 CAS 1809251-51-1
| CAS No. | 1809251-51-1 |
| Molecular Formula | - |
| Molecular Weight | 511.62 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 511.62 g/mol gives Abemaciclib-d5 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Abemaciclib-d5 (CAS 1809251-51-1) is a high-purity analytical reference standard with the molecular formula C27H27D5F2N8 and a molecular weight of 511.62 g/mol.
Structurally, Abemaciclib-d5 (C27H27D5F2N8) contains deuterium isotope labeling, a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 17.5, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 511.62 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C27H27D5F2N8 |
| Molecular Weight | 511.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 17.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib-D8 (CAS 2088650-53-5)
- Abemaciclib Impurity 56 (CAS CATO-C4X-293756)
- Abemaciclib Impurity 139 (CAS CATO-C4X-2937139)
- Abemaciclib Impurity 94 (CAS CATO-C4X-293794)
- Abemaciclib (CAS 1231929-97-7)
- Abemaciclib Impurity 14 (CAS CATO-C4X-293714)
- Abemaciclib Impurity 82 (CAS CATO-C4X-293782)
- Abemaciclib Impurity 122 (CAS CATO-C4X-2937122)
Recommended Standards
- Atrasentan Impurity 15 (CAS 1063836-09-8)
- Methyl 2-((4-butyl-5-((2'-cyano-[1,1'-biphenyl]-4-yl)methyl)-2-methyl-6-oxopyrimidin-1(6H)-yl)methyl)thiophene-3-carboxylate (CAS 172292-52-3)
- Almonertinib Impurity 1 (CAS 1899922-04-3)
- Saxagliptin Impurity 80 (CAS CATO-C4X-104980)
- 1-(4-Bromo-7-methoxybenzofuran-2-yl)ethanone (CAS 192381-08-1)
- Methyl 4-[(2-methoxy-2-oxoethyl)sulfanyl]-1-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridazine-3-carboxylate (CAS 338396-09-1)
- 1-Bromo-4-(difluoromethyl)-2-(trifluoromethoxy)benzene (CAS 2167351-62-2)
- Trimethyl((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)prop-2-yn-1-yl)oxy)silane (CAS 1422378-43-5)
- methyl 2-bromo-2-(4-methoxyphenyl)acetate (CAS 50612-99-2)
- 2-(tert-Butoxy)-1-chloro-4-cyclopropoxybenzene (CAS 1243371-33-6)
- 3,5-Dimethylphenylhydrazine Hydrochloride (CAS 60481-36-9)
- {4-[(4-Chlorophenyl)sulfanyl]phenyl}methanol (CAS 676439-98-8)
- trans-2-(p-Tolyl)cyclopropan-1-amine hydrochloride (CAS 26568-29-6)
- Glucagon Monohydrochloride (CAS 28270-04-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com