Abemaciclib Impurity 122 CAS CATO-C4X-2937122
| CAS No. | CATO-C4X-2937122 |
| Molecular Formula | C28H37FN8 |
| Molecular Weight | 504.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 504.65 g/mol gives Abemaciclib Impurity 122 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Abemaciclib Impurity 122 (CAS CATO-C4X-2937122) is a certified pharmaceutical impurity reference standard with the molecular formula C28H37FN8 and a molecular weight of 504.65 g/mol.
Based on its molecular formula C28H37FN8, Abemaciclib Impurity 122 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 504.65 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 122 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H37FN8 |
| Molecular Weight | 504.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 8 |
Related Abemaciclib Standards
- Abemaciclib Impurity 82 (CAS CATO-C4X-293782)
- Abemaciclib (CAS 1231929-97-7)
- Abemaciclib Impurity 14 (CAS CATO-C4X-293714)
- Abemaciclib Impurity 94 (CAS CATO-C4X-293794)
- Abemaciclib Impurity 139 (CAS CATO-C4X-2937139)
- Abemaciclib Impurity 56 (CAS CATO-C4X-293756)
- Abemaciclib-d5 (CAS 1809251-51-1)
- Abemaciclib-D8 (CAS 2088650-53-5)
Recommended Standards
- a-L-Rhamnopyranosyl-beta-hydroxydecanoyl-beta-hydroxydecanoic acid (CAS 37134-61-5)
- N-Hexanoic-Try-Ile-(6)-amino Hexanoic amide (Dihexa) (CAS 1401708-83-5)
- Teludipine-d6 (CAS 1246833-02-2)
- 4,4'-BIs((e)-4-(tert-butoxy)styryl)-2,2'-bipyridine (CAS 1688673-56-4)
- Norepinephrine Impurity 97 (CAS CATO-C4X-151497)
- Fingolimod EP Impurity F (CAS CATO-C4X-164632)
- Bisoprolol Impurity 107 (CAS CATO-C4X-1247107)
- (3R,4S)-4-(6-fluorobenzofuran-5-yl)-2-oxopyrrolidine-3-carboxylic acid (CAS 1784748-02-2)
- 4-Chloro-2-(((2-methylbenzyl)amino)methyl)phenol (CAS 1183115-88-9)
- 1-(1-(Cyclopropylmethyl)-1H-pyrazol-4-yl)-2,2,2-trifluoroethan-1-one (CAS 1342653-91-1)
- 1-Benzyl-3-(2-methylphenyl)-1h-pyrazol-5-amine (CAS 926246-73-3)
- (S)-7-Chloro-2,3-dihydro-1H-inden-1-ol (CAS 1270301-79-5)
- 10-Propoxy-decanoicacid (CAS 119290-12-9)
- a2,3-Sialylglycopeptide (CAS 189035-43-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com