Abemaciclib Impurity 94 CAS CATO-C4X-293794
| CAS No. | CATO-C4X-293794 |
| Molecular Formula | C25H27F2N9O |
| Molecular Weight | 507.54 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Abemaciclib Impurity 94 (CAS CATO-C4X-293794), a pharmacopoeial impurity reference standard (molecular formula C25H27F2N9O, MW 507.54 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Abemaciclib Impurity 94 (C25H27F2N9O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 16.0, corresponding to approximately 16 ring(s) or double-bond equivalent(s). With a molecular weight of 507.54 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Abemaciclib Impurity 94 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H27F2N9O |
| Molecular Weight | 507.54 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Abemaciclib Standards
- Abemaciclib Impurity 139 (CAS CATO-C4X-2937139)
- Abemaciclib (CAS 1231929-97-7)
- Abemaciclib Impurity 14 (CAS CATO-C4X-293714)
- Abemaciclib Impurity 82 (CAS CATO-C4X-293782)
- Abemaciclib Impurity 56 (CAS CATO-C4X-293756)
- Abemaciclib Impurity 122 (CAS CATO-C4X-2937122)
- Abemaciclib-d5 (CAS 1809251-51-1)
- Abemaciclib-D8 (CAS 2088650-53-5)
Recommended Standards
- Roxadustat Impurity 70 (CAS CATO-C4X-221370)
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- Cabozantinib-d6 (CAS 1802168-46-2)
- Fmoc-Gly-Pro-Hyp-OH (CAS 185213-75-6)
- Naltrexone Impurity 23 (CAS 102272-79-7)
- Erlotinib Impurity 103 (CAS 299912-61-1)
- Elinzanetant Impurity 2 (CAS CATO-C4X-31572)
- Tetrahydropyran-4-sulfonyl Chloride (CAS 338453-21-7)
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- Ethyl 2-oxo-6-((phenylsulfonyl)methyl)-4-(p-tolyl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate (CAS 902277-65-0)
- tert-Butyl 4-chloro-6,7-dihydropyrido[2,3-d]pyrimidine-8(5H)-carboxylate (CAS 1260669-83-7)
- 3-Bromo-4-chloro-8-methylquinoline (CAS 1204810-49-0)
- Methyl 4,6-dimethylnicotinate (CAS 69971-44-4)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com