Betamethasone Impurity 129 CAS CATO-C4X-1437129
| CAS No. | CATO-C4X-1437129 |
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Betamethasone Impurity 129 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Betamethasone Impurity 129 (CAS CATO-C4X-1437129) is a certified pharmaceutical impurity reference standard with the molecular formula C21H27FO4 and a molecular weight of 362.44 g/mol.
Structurally, Betamethasone Impurity 129 (C21H27FO4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 362.44 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 128 (CAS CATO-C4X-1437128)
- Betamethasone Impurity 50 (CAS 1203841-45-5)
- Betamethasone impurity 73 (CAS 1203841-43-3)
- Betamethasone Impurity 75 (CAS CATO-C4X-143775)
- Betamethasone Impurity 94 (CAS 19784-87-3)
- Betamethasone EP Impurity J (CAS 18383-24-9)
- Betamethasone EP Impurity C (CAS 13504-15-9)
- Betamethasone EP Impurity F (CAS 330157-04-5)
Recommended Standards
- Nilotinib Impurity 13 (CAS CATO-C4X-125613)
- Dexamethasone impurity 89 (CAS CATO-C4X-116589)
- Raloxifene Impurity 3 (CAS 1677681-02-5)
- Dexamethasone Impurity 33 (CAS 75262-69-0)
- Trelagliptin Impurity 29 (CAS 1917324-15-2)
- Tolvaptan Impurity 45 (CAS 2458812-60-5)
- Cefdinir Impurity 36 (CAS CATO-C4X-121036)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com