Betamethasone Impurity 128 CAS CATO-C4X-1437128
| CAS No. | CATO-C4X-1437128 |
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO supplies Betamethasone Impurity 128 (CAS CATO-C4X-1437128), a pharmacopoeial impurity reference standard (molecular formula C21H27FO4, MW 362.44 g/mol) used for the identification and quantification of trace impurities in APIs.
Betamethasone Impurity 128 (C21H27FO4) contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO manufactures Betamethasone Impurity 128 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H27FO4 |
| Molecular Weight | 362.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Betamethasone Standards
- Betamethasone Impurity 129 (CAS CATO-C4X-1437129)
- Betamethasone Impurity 50 (CAS 1203841-45-5)
- Betamethasone impurity 73 (CAS 1203841-43-3)
- Betamethasone Impurity 75 (CAS CATO-C4X-143775)
- Betamethasone Impurity 94 (CAS 19784-87-3)
- Betamethasone EP Impurity J (CAS 18383-24-9)
- Betamethasone EP Impurity C (CAS 13504-15-9)
- Betamethasone EP Impurity F (CAS 330157-04-5)
Recommended Standards
- Nilotinib Impurity 13 (CAS CATO-C4X-125613)
- Dexamethasone impurity 89 (CAS CATO-C4X-116589)
- Dexamethasone Impurity 33 (CAS 75262-69-0)
- Febuxostat Impurity 73 (CAS 1346238-15-0)
- Butenafine Impurity 17 (CAS CATO-C4X-159617)
- Etizolam Impurity C62 (CAS 16437-59-5)
- Azilsartan Impurity 51 (CAS 139481-38-2)
- 2,3-Dihydrospiro[cyclopropane-1,4(1H)-isoquinolin]-1-one (CAS 1782267-00-8)
- (5,7-Dichloro-2,3-dihydrobenzofuran-4-yl)boronic acid (CAS 1046861-87-3)
- 5-Fluoro-2-(methylsulfinyl)benzo[d]thiazole (CAS 1271024-87-3)
- ((3AR,6aS)-hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl)(tetrahydro-2H-pyran-4-yl)methanone (CAS 1689944-16-8)
- Ilaprazole Impurity 25 (CAS CATO-C4X-113025)
- 5-Fluoronaphthalen-1-amine (CAS 13720-49-5)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com