Vonoprazan Fumarate Impurity 17 CAS 1883595-38-7
| CAS No. | 1883595-38-7 |
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Vonoprazan Fumarate Impurity 17 is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
Vonoprazan Fumarate Impurity 17 (CAS 1883595-38-7) is a certified pharmaceutical impurity reference standard with the molecular formula C11H8FNO2 and a molecular weight of 205.19 g/mol.
Structurally, Vonoprazan Fumarate Impurity 17 (C11H8FNO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 205.19 g/mol, it falls into the medium-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Vonoprazan Fumarate Impurity 17 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H8FNO2 |
| Molecular Weight | 205.19 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1995 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Vonoprazan Standards
- Vonoprazan Impurity 196 (CAS CATO-C4X-1020196)
- Vonoprazan Impurity 244 (CAS CATO-C4X-1020244)
- Vonoprazan Impurity 65 (CAS 1610043-62-3)
- Vonoprazan Impurity 113 (CAS 1956309-28-6)
- Vonoprazan Impurity 173 (CAS CATO-C4X-1020173)
- Vonoprazan Impurity 142 (CAS CATO-C4X-1020142)
- Vonoprazan Impurity 217 (CAS 16420-39-6)
- Vonoprazan Impurity 307 (CAS CATO-C4X-1020307)
Recommended Standards
- Fluconazole Impurity 50 (CAS 58905-21-8)
- 6-Fluoro-2-methyl-quinoline-4-carboxylic acid 6-fluoro-2-methyl-4-quinolinecarboxylic acid 6-fluoro-2-methylquinoline-4-carboxylic acid 716-03-0 (CAS 716-03-0)
- 3990AE 461026-47-1 6-Fluoro-2-methyl-quinoline-3-carboxylic acid C11H8FNO2 (CAS 461026-47-1)
- 3',4'-Difluoro-[1,1'-biphenyl]-4-amine (CAS 1184136-90-0)
- Flunarizine Impurity 12 (CAS 88172-16-1)
- Argatroban Impurity 88 (CAS CATO-C4X-100788)
- Calcitriol Impurity 23 (CAS CATO-C4X-151023)
- 5-Chloro-1H-pyrazolo[3,4-c]pyridin-3-amine (CAS 245325-32-0)
- [3-(6-Bromo-pyridin-2-yl)-isoxazol-5-yl]-methanol (CAS 1199773-57-3)
- (4-(8-(Cyclopropylamino)imidazo[1,2-a]pyrazin-3-yl)phenyl)methanol (CAS 825630-01-1)
- N-(5-Chloro-2-hydroxyphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1022206-23-0)
- 1,1-Dioxo-2,3-dihydro-1lambda6-benzothiophene-3-carboxylic acid (CAS 14750-57-3)
- N-(3-Bromo-5-trifluoromethyl-pyridin-2-yl)-N,N-dimethyl-ethane-1,2-diamine (CAS 1311280-05-3)
- Liraglutide (CAS 204656-20-2)
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