Ezetimibe Impurity 36 CAS 189028-93-1
| CAS No. | 189028-93-1 |
| Molecular Formula | C20H18FNO4 |
| Molecular Weight | 355.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 355.36 g/mol gives Ezetimibe Impurity 36 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Ezetimibe Impurity 36 (CAS 189028-93-1) is a certified pharmaceutical impurity reference standard with the molecular formula C20H18FNO4 and a molecular weight of 355.36 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Ezetimibe Impurity 36 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 355.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Ezetimibe Impurity 36 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H18FNO4 |
| Molecular Weight | 355.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 38 (CAS 404874-93-7)
- Ezetimibe Impurity 87 (CAS 2514695-40-8)
- Ezetimibe Impurity 92 (CAS 2469633-86-9)
- Ezetimibe Impurity 125 (CAS 439080-96-3)
- Ezetimibe Impurity 139 (CAS CATO-C4X-1098139)
- Ezetimibe Impurity 24 (CAS 528565-93-7)
- Ezetimibe Impurity 25 (CAS 404874-94-8)
- Ezetimibe Impurity 26 (CAS 1612153-32-8)
Recommended Standards
- Linezolid Impurity 11 (CAS 1394245-06-7)
- (R)-3-(hexanoyloxy)-2-hydroxypropyl 2-(trimethylammonio)ethyl phosphate 1-Caproyl-2-hydroxy-Sn-glycero-3-phosphocholine 58445-96-8 (CAS 58445-96-8)
- S-Hydroxy Topiramate (CAS 198215-62-2)
- Biapenem-13C2,15N3 (CAS 120410-24-4 (unlabeled))
- 4-Chloro-3-sulfobenzoic acid (Bumetanide Impurity) (CAS 755698-62-5)
- Belumosudil Impurity 44 (CAS CATO-C4X-298844)
- Tolterodine Impurity 39 (CAS CATO-C4X-176739)
- 4-(3-bromothiophen-2-yl)-N-methylpyrimidin-2-amine (CAS 1516757-44-0)
- 1-(6-Chloropyrazin-2-yl)-N,N-dimethylmethanamine dihydrochloride (CAS 1609400-33-0)
- 4-Chloro-6-propylthieno[2,3-d]pyrimidine (CAS 439692-82-7)
- (5S)-4-oxa-1-azabicyclo[3.3.1]nonan-6-one (CAS 1542160-38-2)
- 4-(Chloromethyl)-1,2-dihydroisoquinolin-1-one (CAS 2092777-38-1)
- 3-(1-Acetylpiperidin-4-yl)propanoic acid (CAS 131417-49-7)
- Semaglutide impurity 66 (CAS CATO-C4X-222666)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com