Ketoprofen Impurity 112 CAS 42872-32-2

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.42872-32-2
Molecular FormulaC9H6ClNO
Molecular Weight179.60 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Ketoprofen Impurity 112 CAS 42872-32-2 chemical structure

Description

As a certified reference material (CRM), Ketoprofen Impurity 112 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies Ketoprofen Impurity 112 (CAS 42872-32-2), a pharmacopoeial impurity reference standard (molecular formula C9H6ClNO, MW 179.60 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Ketoprofen Impurity 112 (C9H6ClNO) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC9H6ClNO
Molecular Weight179.60 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity≥95%
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)7.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1969
Halogen ContentCl-containing
Nitrogen Atoms1

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