Ezetimibe ketone CAS 191330-56-0
| CAS No. | 191330-56-0 |
| Molecular Formula | C24H19F2NO3 |
| Molecular Weight | 407.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Ezetimibe ketone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Ezetimibe ketone (CAS 191330-56-0) is a high-purity analytical reference standard with the molecular formula C24H19F2NO3 and a molecular weight of 407.41 g/mol.
The molecular framework of Ezetimibe ketone (C24H19F2NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C24H19F2NO3 |
| Molecular Weight | 407.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2011 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Ezetimibe Standards
- Ezetimibe Impurity 72 (CAS CATO-C4X-109872)
- Ezetimibe Impurity 33 (CAS 1700622-07-6)
- Ezetimibe Impurity ((S)-4-Phenyloxazolidin-2-one) Sodium salt (CAS 200067-49-8)
- Ezetimibe (CAS 163222-33-1)
- Ezetimibe meta-Fluorobenzene Isomer (CAS CATO-C4X-1098127)
- Ezetimibe Lactone Impurity 128 (CAS CATO-C4X-1098128)
- Ezetimibe Impurity 17(SCH59566) (CAS 1296129-15-1)
- Ezetimibe Ring-Opening Dehydrate Impurity (CAS 1292292-63-7)
Recommended Standards
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- NHS-PEG6 (CAS 216145-65-2)
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- 3-(4-Fluorophenyl)-1-m-tolyl-1h-pyrazole-5-carboxylic acid (CAS 618102-87-7)
- 2-(Azetidin-3-yloxy)-N-isopropyl-N-methylacetamide (CAS 1339473-45-8)
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- 2-Amino-6-(hydroxymethyl)-8-oxo-4-(pyridin-3-yl)-4H,8H-pyrano[3,2-b]pyran-3-carbonitrile (CAS 625376-09-2)
- 1-(3,4-Dichlorophenyl)-2-(2,3-dihydro-1h-inden-5-yloxy)ethan-1-one (CAS 1154284-20-4)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
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