Nicergoline EP Impurity H CAS 192504-81-7
| CAS No. | 192504-81-7 |
| Molecular Formula | C23H24BrN3O3 |
| Molecular Weight | 470.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Nicergoline EP Impurity H (C23H24BrN3O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 470.36 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Nicergoline EP Impurity H (CAS 192504-81-7), a pharmacopoeial impurity reference standard (molecular formula C23H24BrN3O3, MW 470.36 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nicergoline EP Impurity H under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H24BrN3O3 |
| Molecular Weight | 470.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2012 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Nicergoline Standards
- Nicergoline Impurity 15 (CAS CATO-C4X-208515)
- Nicergoline EP Impurity B (CAS 35264-46-1)
- Nicergoline EP Impurity E (CAS 57935-66-7)
- Nicergoline (CAS 27848-84-6)
- Nicergoline Impurity 26 (CAS CATO-C4X-208526)
- Nicergoline EP Impurity F (CAS 58001-19-7)
- Nicergoline EP Impurity G (CAS 57935-65-6)
- Nicergoline-13C-d3 (CAS CATO-C4X-208513)
Recommended Standards
- (E)-{[4-(4-chlorophenyl)-7-thia-2,5-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(8),3,5-trien-3-yl]methylidene}amino 4-chlorobenzoate (CAS 478041-88-2)
- (E)-2-(4-chlorophenyl)-5,6,7,8-tetrahydrobenzo[d]imidazo[2,1-b]thiazole-3-carbaldehyde O-(2-chlorobenzoyl) oxime (CAS 478041-91-7)
- Ethyl 2-({4-[5-chloro-1-(3-chlorophenyl)-6-oxo-1,6-dihydropyridazin-4-yl]piperazine-1-carbothioyl}amino)acetate (CAS 477867-35-9)
- Beclometasone Impurity 38 (CAS CATO-C4X-147438)
- Trimetazidine Impurity 29 (CAS CATO-C4X-180329)
- Alfacalcidol impurity 10 (CAS 174176-73-9)
- Paliperidone Impurity 34 (CAS CATO-C4X-1724134)
- 6,8-Dimethylisoquinolin-3-amine (CAS 1192815-04-5)
- N-(2-methyl-1-phenylpropyl)hydroxylamine (CAS 887411-41-8)
- 2-[4-Amino(ethyl)-2-fluoroanilino]-1-ethanol (CAS 1179154-46-1)
- Tiotropium Bromide Impurity 8 Potassium Salt (CAS 10304-09-3)
- 1,3-Dimethyl-2-(4-nitrophenyl)-1H-benzo[d]imidazol-3-ium iodide (CAS 3717-95-1)
- Ethyl 4-(5-hydroxypyridin-3-yl)benzoate (CAS 1261945-50-9)
- Staphylococcus Aureus Protein A (SpA)-Derived Peptide (H-2228.0005) (CAS 144979-26-0)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com