Nicergoline EP Impurity F CAS 58001-19-7
| CAS No. | 58001-19-7 |
| Molecular Formula | C24H26BrN3O3 |
| Molecular Weight | 484.39 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Nicergoline EP Impurity F (C24H26BrN3O3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a process- or degradation-related impurity, Nicergoline EP Impurity F (CAS 58001-19-7, C24H26BrN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Nicergoline EP Impurity F under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H26BrN3O3 |
| Molecular Weight | 484.39 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1973 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 3 |
Related Nicergoline Standards
- Nicergoline (CAS 27848-84-6)
- Nicergoline Impurity 26 (CAS CATO-C4X-208526)
- Nicergoline-13C-d3 (CAS CATO-C4X-208513)
- Nicergoline Impurity 15 (CAS CATO-C4X-208515)
- Nicergoline EP Impurity B (CAS 35264-46-1)
- Nicergoline EP Impurity E (CAS 57935-66-7)
- Nicergoline EP Impurity H (CAS 192504-81-7)
- Nicergoline Impurity 17 (CAS CATO-C4X-208517)
Recommended Standards
- (5-((4-Chlorophenyl)thio)-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl (3-chlorophenyl)carbamate (CAS 318248-31-6)
- N-(2-Chloro-4,6-dimethylphenyl)-2-((4-(4-chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 476483-97-3)
- Palbociclib Impurity 187 (CAS CATO-C4X-1125187)
- N-(2-chlorophenyl)-2-((5-(((4-chlorophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332930-62-8)
- Bempedoic Acid Impurity 26 (CAS CATO-C4X-218926)
- Ixazomib Impurity 7 (CAS CATO-C4X-12677)
- Propranolol impurity 44 (CAS CATO-C4X-151944)
- 2-Methyl-2-(benzylthio)propylamine (CAS 59681-09-3)
- 2-Cyanobutan-2-yl 3,5-dimethyl-1H-pyrazole-1-carbodithioate (CAS 1883264-36-5)
- 4-Isopropoxy-3,5-dimethoxybenzonitrile (CAS 1219828-05-3)
- 2-[5-(2-Methylpropyl)-1,2,4-oxadiazol-3-yl]piperidine hydrochloride (CAS 1385696-81-0)
- 4,5-Dibromo-1,1,1,2,2,3,3-heptafluoropentane (CAS 377-46-8)
- N-[2-(Dimethylamino)ethyl]acrylamide(stabilizedwithMEHQ) (CAS 925-76-8)
- Liraglutide (CAS 204656-20-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com