Rivaroxaban Impurity 125 CAS 19298-14-7

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.19298-14-7
Molecular FormulaC8H12N2O
Molecular Weight152.19 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Rivaroxaban Impurity 125 CAS 19298-14-7 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 152.19 g/mol gives Rivaroxaban Impurity 125 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

Rivaroxaban Impurity 125 (CAS 19298-14-7) is a certified pharmaceutical impurity reference standard with the molecular formula C8H12N2O and a molecular weight of 152.19 g/mol.

Rivaroxaban Impurity 125 (C8H12N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC8H12N2O
Molecular Weight152.19 g/mol
AppearanceOff-white to pale yellow crystalline powder. (faint amine-like odor)
Purity>95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)1962
Nitrogen Atoms2

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