Nintedanib Impurity 51 (Z-Isomer) CAS 2102162-79-6
| CAS No. | 2102162-79-6 |
| Molecular Formula | C22H22N2O3 |
| Molecular Weight | 362.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H22N2O3, Nintedanib Impurity 51 (Z-Isomer) contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 362.42 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO supplies Nintedanib Impurity 51 (Z-Isomer) (CAS 2102162-79-6), a pharmacopoeial impurity reference standard (molecular formula C22H22N2O3, MW 362.42 g/mol) used for the identification and quantification of trace impurities in APIs.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Nintedanib Impurity 51 (Z-Isomer) meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H22N2O3 |
| Molecular Weight | 362.42 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1997 |
| Nitrogen Atoms | 2 |
Related Nintedanib Standards
- Nintedanib Impurity 26 (CAS CATO-C4X-181426)
- Nintedanib Impurity 162 (CAS CATO-C4X-1814162)
- Nintedanib Impurity 34 (CAS 1235004-99-5)
- Nintedanib Impurity 24 (CAS CATO-C4X-181424)
- Nintedanib Impurity 188 (CAS 2676997-47-8)
- Nintedanib Impurity 148 (CAS CATO-C4X-1814148)
- Nintedanib Impurity 13 (CAS 1253769-13-9)
- Nintedanib Impurity 49 (CAS 1168152-07-5)
Recommended Standards
- Rotigotine Impurity 38 (CAS CATO-C4X-192738)
- Pentoxifylline EP Impurity H (CAS 200556-62-3)
- Roxadustat Impurity 158 (CAS CATO-C4X-2213158)
- Terbutaline Sulphate Impurity 50 (CAS 50841-46-8)
- Ebastine EP Impurity F (CAS 1429071-63-5)
- Nimesulide EP Impurity E (CAS 905858-63-1)
- Valsartan Impurity 104 (CAS CATO-C4X-1057104)
- N-((1r,4r)-4-Aminocyclohexyl)propionamide (CAS 1286319-95-6)
- piperidin-2-ylmethyl N-cyclopentylcarbamate hydrochloride (CAS 1803571-17-6)
- Celecoxib-d4 (CAS 544686-20-6)
- 5-(METHYLTHIO)-2,3-DIHYDRO-1H-INDEN-1-ONE (CAS 218452-81-4)
- 1-(Benzo[d][1,3]dioxol-5-ylcarbamoyl)piperidine-4-carboxylic acid (CAS 866132-02-7)
- 7-chloropyrazolo[1,5-a]pyrimidin-5-amine (CAS 1189852-04-7)
- Peptide-GMF (CAS CATO-CPTD788469)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com