Tenofovir Disoproxil Impurity 44 CAS 201340-97-8
| CAS No. | 201340-97-8 |
| Molecular Formula | C18H28N5O10P |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Tenofovir Disoproxil Impurity 44 (CAS 201340-97-8), a pharmacopoeial impurity reference standard (molecular formula C18H28N5O10PC4H4O4, MW 621.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Owing to a flavonoid core, an amide group, a phosphate ester group, a hydroxyl group, an ether linkage, Tenofovir Disoproxil Impurity 44 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 621.49 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Tenofovir Disoproxil Impurity 44 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H28N5O10P C4H4O4 |
| Molecular Weight | 621.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2014 |
| Nitrogen Atoms | 5 |
Related Tenofovir Standards
- Tenofovir alafenamide Impurity 79 (CAS 102-10-3)
- rac Tenofovir-d6 (CAS 1020719-94-1)
- Tenofovir disoproxil Impurity 142 (CAS 102537-97-3)
- Tenofovir Disoproxil Dimer (CAS 1093279-76-5)
- Tenofovir disoproxil Impurity 6 (CAS 1093279-77-6)
- Tenofovir disoproxil Impurity 28 (CAS 1115-59-9)
- Tenofovir Impurity 59 (CAS 116384-56-6)
- Tenofovir alafenamide impurity 85 (CAS 121149-98-2)
Recommended Standards
- Indacaterol Impurity 19 (CAS 1454818-75-7)
- Tofacitinib Impurity 152 (CAS CATO-C4X-1079152)
- Perindopril Impurity 80 HCl (CAS CATO-C4X-125280)
- (4,5-Difluoro-2-methoxyphenyl)methanol (CAS 886761-72-4)
- 2-Amino-3-phenylbutanoic acid (CAS 2260-12-0)
- n-Ethyl-2,3-difluoroaniline (CAS 1247537-10-5)
- N1-(2,2-Diethoxyethyl)-N2-(3-fluorophenyl)oxalamide (CAS 898357-85-2)
- 6-(Thiophen-3-yl)-9H-purine (CAS 918537-12-9)
- 4-Hydroxy-3'-methoxy-[1,1'-biphenyl]-3-carboxylic acid (CAS 400749-59-9)
- Acetyl Tetrapeptide-11 (CAS 928006-88-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com