Olaparib Impurity 163 CAS 1460272-52-9
| CAS No. | 1460272-52-9 |
| Molecular Formula | C24H21FN4O4 |
| Molecular Weight | 448.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C24H21FN4O4, Olaparib Impurity 163 contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 448.45 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies Olaparib Impurity 163 (CAS 1460272-52-9), a pharmacopoeial impurity reference standard (molecular formula C24H21FN4O4, MW 448.45 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Olaparib Impurity 163 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H21FN4O4 |
| Molecular Weight | 448.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Olaparib Standards
- Olaparib Impurity 9 (CAS CATO-C4X-11359)
- Olaparib Impurity 120 (CAS CATO-C4X-1135120)
- Olaparib Impurity 21 (CAS CATO-C4X-1135121)
- Olaparib Impurity 151 (CAS CATO-C4X-1135151)
- Olaparib Impurity 7 (CAS CATO-C4X-11357)
- Olaparib Impurity 10 (CAS CATO-C4X-113510)
- Olaparib Impurity 160 (CAS CATO-C4X-1135160)
- Olaparib Impurity 118 (CAS CATO-C4X-1135118)
Recommended Standards
- Apremilast Impurity 52 (CAS CATO-C4X-100952)
- Apremilast Impurity 38 (CAS 2095036-40-9)
- Doxycycline-13C-d3 (CAS CATO-C4X-193111)
- Apremilast Impurity 36 (CAS 253168-82-0)
- Cabozantinib Impurity 14 (CAS CATO-C4X-201814)
- Neostigmine impurity 44 (CAS CATO-C4X-204244)
- Safinamide Impurity 2 (CAS 1160513-60-9)
- (1S,3S)-cyclopentane-1,3-dicarboxylic acid (CAS 36010-89-6)
- N1-Azepan-4-yl-N2,N2-dimethylglycinamide dihydrochloride (CAS 2108705-42-4)
- Lansoprazole Impurity 36 (CAS 58536-71-3)
- Ethyl 6-methyl-3-isoquinolinecarboxylate (CAS 412010-12-9)
- 3-bromopyrrolidineHCl (CAS 952748-39-9)
- 7-(3-Aminoazepan-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid (CAS 141388-65-0)
- Glucagon (1-29) (CAS 16941-32-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com