2-Chloro-3,6-difluorophenylboronic acid CAS 2377608-42-7
| CAS No. | 2377608-42-7 |
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-Chloro-3,6-difluorophenylboronic acid is closely related to a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies 2-Chloro-3,6-difluorophenylboronic acid (CAS 2377608-42-7), a certified reference material (molecular formula C6H4BClF2O2, MW 192.36 g/mol) for analytical method development and quality control.
Based on its molecular formula C6H4BClF2O2, 2-Chloro-3,6-difluorophenylboronic acid contains a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 192.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-Chloro-3,6-difluorophenylboronic acid meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C6H4BClF2O2 |
| Molecular Weight | 192.36 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| CAS Registry Year (est.) | 1999 |
| Halogen Content | F/Cl-containing |
Related Chloro Standards
- (3-Chloro-2,6-difluorophenyl)boronic acid (CAS 1031226-45-5)
- (4-Chloro-2,3-difluorophenyl)boronic acid (CAS 1160561-28-3)
- (3-Chloro-2,4-difluorophenyl)boronic acid (CAS 1310384-18-9)
- 2-Chloro-4,6-difluorophenylboronic Acid (CAS 1373393-48-6)
- (2-Chloro-3,5-difluorophenyl)boronic acid (CAS 1451393-37-5)
- (3-Chloro-4,5-difluorophenyl)boronic acid (CAS 1643467-84-8)
- 2-Chloro-4,5-difluorophenylboronic acid (CAS 1801916-39-1)
- (4-Chloro-2,6-difluorophenyl)boronic acid (CAS 925911-61-1)
Recommended Standards
- 2-Chloro-3,4-difluorophenylboronic acid (CAS 2121511-30-4)
- 3-Chloro-2,5-difluorophenylboronic acid (CAS 2377610-17-6)
- 4-Chloro-2,5-difluorophenylboronic acid (CAS 2055778-26-0)
- 4-Chloro-3,5-difluorophenylboronic Acid (CAS 864759-63-7)
- 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10-Icosafluorodecane (CAS 3492-24-8)
- tert-Butyl 4-aminopyridine-2-carboxylate (CAS 868171-68-0)
- Ethyl 3-amino-4-chloro-2-nitrobenzoate (CAS 1277132-56-5)
- 4-(4-methylpiperidin-1-yl)butan-1-amine (CAS 900717-45-5)
- 1-(3-Propyl-1H-pyrrol-2-yl)ethanone (CAS 66786-07-0)
- 1H-Spiro[furo[3,4-c]pyridine-3,4'-piperidine] hydrochloride (CAS 1224895-26-4)
- 2,7-Dimethoxy-9-mesityl-10-methylacridinium tetrafluoroborate (CAS 2635339-81-8)
- 3-((1-Methylpiperidin-4-yl)oxy)propanoic acid (CAS 1340250-98-7)
- Methyl 2-((5-bromo-2-formylphenyl)thio)acetate (CAS 1341391-39-6)
- Tau Peptide (294-305) (human) trifluoroacetate salt (CAS 1428135-29-8)
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