Bedaquiline Impurity 54 CAS CATO-C4X-116754
| CAS No. | CATO-C4X-116754 |
| Molecular Formula | C29H24BrNO2 |
| Molecular Weight | 498.41 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Bedaquiline Impurity 54.
CATO supplies Bedaquiline Impurity 54 (CAS CATO-C4X-116754), a pharmacopoeial impurity reference standard (molecular formula C29H24BrNO2, MW 498.41 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Bedaquiline Impurity 54 (C29H24BrNO2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 18.0, corresponding to approximately 18 ring(s) or double-bond equivalent(s). With a molecular weight of 498.41 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Bedaquiline Impurity 54 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C29H24BrNO2 |
| Molecular Weight | 498.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Bedaquiline Standards
- Bedaquiline Impurity 32 (CAS CATO-C4X-116732)
- Bedaquiline Impurity 33 (CAS CATO-C4X-116733)
- Bedaquiline Impurity 34 (CAS CATO-C4X-116734)
- Bedaquiline Impurity 35 (CAS CATO-C4X-116735)
- Bedaquiline Impurity N21 (CAS 1298044-25-3)
- Bedaquiline Impurity 22 (CAS 1849588-75-5)
- Bedaquiline Impurity 38 (CAS CATO-C4X-116738)
- Bedaquiline Impurity 8 (CAS 2122862-01-3)
Recommended Standards
- 1-{[3,5-bis(trifluoromethyl)phenyl]methyl}-4-[5-(3-nitrophenyl)-1H-pyrazol-3-yl]piperidine (CAS 1025724-72-4)
- Melphalan Flufenamide (CAS 380449-51-4)
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4,5,6,7-tetrafluoro-1H-indol-3-yl)propanoic acid (CAS 281655-59-2)
- N-(2,3-dichlorophenyl)-2-((4-phenyl-5-((p-tolylamino)methyl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332907-22-9)
- Atrasentan Impurity 98 (CAS 1059043-59-2)
- Epalrestat impurity 37 (CAS CATO-C4X-223637)
- Clopidogrel Impurity 113 (CAS 16694-46-5)
- Methyl (2Z)-3-[(4-ethoxyphenyl)amino]-2-(4-ethylbenzenesulfonyl)prop-2-enoate (CAS 1327176-85-1)
- 4-Chloro-N-ethyl-2-nitroaniline (CAS 28491-95-4)
- (2R,3S,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-2-(hydroxymethyl)tetrahydrofuran-3-yl (((2R,3S,5R)-5-(2-amino-6-oxo-3H-purin-9(6H)-yl)-3-hydroxytetrahydrofuran-2-yl)methyl) hydrogen phosphate (CAS 15178-66-2)
- 3-(1-Methyl-1h-indazol-3-yl)propan-1-amine (CAS 1540863-36-2)
- 4-Bromo-5-(isobutoxymethyl)-1-isopropyl-1H-pyrazole (CAS 1856088-95-3)
- 1-(2-Bromo-4-fluorophenyl)pyrrolidin-2-one (CAS 1037150-18-7)
- D-Phe6-Tirzepatide (CAS CATO-CPTD788925)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com