Abemaciclib Impurity N3 CAS 1231930-42-9
| CAS No. | 1231930-42-9 |
| Molecular Formula | C15H13ClF2N4 |
| Molecular Weight | 322.74 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Abemaciclib Impurity N3.
CATO supplies Abemaciclib Impurity N3 (CAS 1231930-42-9), a pharmacopoeial impurity reference standard (molecular formula C15H13ClF2N4, MW 322.74 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C15H13ClF2N4, Abemaciclib Impurity N3 contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 322.74 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H13ClF2N4 |
| Molecular Weight | 322.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1990 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Abemaciclib Standards
- Abemaciclib Impurity 4 (CAS CATO-C4X-29374)
- Abemaciclib Impurity N1 (CAS 2177297-46-8)
- Abemaciclib Impurity N7 (CAS 1231930-37-2)
- Abemaciclib Impurity 140 (CAS 2124229-65-6)
- Abemaciclib Impurity 63 (CAS CATO-C4X-293763)
- Abemaciclib Impurity 123 (CAS CATO-C4X-2937123)
- Abemaciclib Impurity 177 (CAS CATO-C4X-2937177)
- Abemaciclib Impurity 167 (CAS CATO-C4X-2937167)
Recommended Standards
- 4-((4-Chlorophenyl)amino)-3-((furan-2-ylmethyl)amino)-4-oxobutanoic acid (CAS 1022917-31-2)
- Ethyl 2-(4-chloro-5-(4-ethoxyphenyl)-3-oxofuran-2(3H)-ylidene)acetate (CAS 139266-46-9)
- (5-((4-Chlorophenyl)thio)-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methanol (CAS 318239-52-0)
- 5-Chloro-N-(4-Fluorophenyl)-2-Nitro-1-Benzothiophen-3-Amine (CAS 149338-26-1)
- Imatinib Impurity 58 (CAS 125743-63-7)
- Valproate Impurity 37 (CAS 62391-98-4)
- Dotinurad Impurity 191 (CAS CATO-C4X-2494191)
- 4-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl]butanoic acid (CAS 1006461-93-3)
- 2-methylimidazolezincsalt,zif8 59061-53-9 (CAS 59061-53-9)
- 3-Aminomethyl-3-hydroxymethyl-piperidine-1-carboxylic acid tert-butyl ester (CAS 1781936-85-3)
- 2,2',7,7'-Tetramethoxy-9,9'-spirobi[fluorene]-3,3',6,6'-tetraamine (CAS 1801236-36-1)
- 4-Iodo-1-(tetrahydro-2H-pyran-2-yl)-1H-indazole (CAS 956388-08-2)
- 2-Chloro-8-methoxyquinoline-3-carboxylic acid (CAS 1017157-83-3)
- Semaglutide impurity 198 (CAS CATO-C4X-2226198)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com