Fulvestrant EP Impurity E CAS 2170200-14-1
| CAS No. | 2170200-14-1 |
| Molecular Formula | C32H45F5O3S |
| Molecular Weight | 604.75 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Fulvestrant EP Impurity E under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Fulvestrant EP Impurity E (CAS 2170200-14-1, C32H45F5O3S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Fulvestrant EP Impurity E (C32H45F5O3S) contains a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, a polycyclic aromatic system. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 604.75 g/mol, it falls into the high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C32H45F5O3S |
| Molecular Weight | 604.75 g/mol |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1998 |
| Halogen Content | F-containing |
| Sulfur Atoms | 1 |
Related Fulvestrant Standards
- Fulvestrant impurity 36 (CAS CATO-C4X-191736)
- Fulvestrant impurity 53 (CAS CATO-C4X-191753)
- Fulvestrant (CAS 129453-61-8)
- Fulvestrant EP Impurity A (CAS 407577-53-1)
- Fulvestrant S Enantiomer (CAS 1316849-17-8)
- Fulvestrant R Enantiomer (CAS 1807900-80-6)
- Fulvestrant impurity 32 (CAS CATO-C4X-191732)
- Fulvestrant-d3 (CAS CATO-C4X-19177)
Recommended Standards
- 17-Keto Fulvestrant (CAS 403656-89-3)
- H-Leu-Trp-Met-Arg-OH (H-3975.0250) (CAS 67368-23-4)
- S-acetyl-PEG12-alcohol (CAS 165729-83-9)
- Alectinib Impurity 86 (CAS CATO-C4X-283686)
- Indocyanine Green Impurity 33 (CAS CATO-C4X-250333)
- Haloperidol EP Impurity B (CAS 1391052-53-1)
- Lenvatinib Impurity 137 Chloride (CAS 6118-33-8)
- 6,7-Dimethyl-5,6,7,8-tetrahydrotetrazolo[1,5-b][1,2,4]triazine (CAS 384814-90-8)
- N,N-bis(4-bromophenyl)-9,9-dimethyl-9H-fluoren-2-amine (CAS 1216940-51-0)
- RSS0343 Impurity 2 (CAS CATO-C4X-32722)
- Isopropyl 6-hydroxy-5-nitronicotinate (CAS CATO-C3D-263212)
- (6-Bromo-1-methyl-1H-pyrrolo[3,2-b]pyridin-3-yl)methanol (CAS 2231673-28-0)
- 5-(Methylthio)-2H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine (CAS 93886-72-7)
- Semaglutide Impurity 16 (CAS CATO-C4X-222616)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com